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TranscriptomicsHeart RNA-Seq of cardiomyocyte-specific and inducible Prmt5 knockout mouse model, AVV9-ACADVL rescue
Our study introduces a novel animal model featuring a cardiomyocyte-specific, inducible knockout of the Prmt5. The primary aim of this model is to investigate the regulatory mechanisms of PRMT5, the main representative of type II PRMTs. We found that PRMT5 controls Acadvl mRNA splicing, and that dis...
ORGANISM(S): Mus musculus 
2026-05-15 | E-MTAB-14396 | biostudies-arrayexpress
TranscriptomicsHeart RNA-Seq of cardiomyocyte-specific and inducible Prmt5 knockout mouse model, nuclear sequencing without treatment
Our study introduces a novel animal model featuring a cardiomyocyte-specific, inducible knockout of the Prmt5. The primary aim of this model is to investigate the regulatory mechanisms of PRMT5, the main representative of type II PRMTs. We found that PRMT5 controls Acadvl mRNA splicing, and that dis...
ORGANISM(S): Mus musculus 
2026-05-15 | E-MTAB-14401 | biostudies-arrayexpress
TranscriptomicsHeart RNA-Seq of cardiomyocyte-specific and inducible Prmt5 knockout mouse model
Our study introduces a novel animal model featuring a cardiomyocyte-specific, inducible knockout of the Prmt5. The primary aim of this model is to investigate the regulatory mechanisms of PRMT5, the main representative of type II PRMTs. We found that PRMT5 controls Acadvl mRNA splicing and that disr...
ORGANISM(S): Mus musculus 
2026-05-15 | E-MTAB-13594 | biostudies-arrayexpress
TranscriptomicsIdentification of RNA targets of EB1 using RIP-seq in Drosophila ovaries
Identification of RNAs that bind to EB1-GFP using RNA-immunoprecipitation followed by sequencing. Ovaries from flies expressing EB1-GFP (and GFP alone as a control) were used to immunoprecipitate crosslinked RNA-EB1GFP complexes using GFP Trap beads. The experiment was performed with three biologica...
ORGANISM(S): Drosophila melanogaster 
2021-07-24 | E-MTAB-9078 | biostudies-arrayexpress
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