T-cell mediated rejection

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[(9S)-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-h]chromen-9-yl] (Z)-2-methylbut-2-enoate (1)
[(2R)-3-Hexadecoxy-2-hydroperoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate (1)
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Molecular diagnosis of T cell and/or antibody-mediated rejection in human kidney transplant biopsies

Histologic diagnosis of T cell-mediated rejection in kidney transplant biopsies has limited reproducibility because it is based on non-specific lesions using arbitrary rules that are subject to differing interpretations. We used microarray results from 403 indication biopsies previously given histol...

ORGANISM(S): Homo sapiens

2013-02-13 | E-GEOD-36059 | biostudies-arrayexpress

Fuzheng Jiedu Xiaoji Formula Enhances Anti-PD-1 Therapy for Hepatocellular Carcinoma by Inhibiting Regulatory T Cell Lipotoxicity

Background: The objective response rate of anti-programmed death receptor 1 (PD-1) immunotherapy in hepatocellular carcinoma (HCC) remains limited. The tumor immunosuppressive microenvironment mediated by regulatory T cells (Tregs) is a key bottleneck. The traditional Chinese medicine (TCM) compo...

2025-12-05 | MTBLS13458 | MetaboLights

Assessing rejection-related disease in kidney transplant biopsies based on archetypal analysis of molecular phenotypes

Molecular phenotyping of biopsies affords opportunities for increased precision and improved disease classification to address the limitations of conventional histologic diagnostic systems. We applied archetypal analysis, an unsupervised method similar to cluster analysis, to microarray data from 12...

ORGANISM(S): Homo sapiens

2017-07-10 | E-GEOD-98320 | biostudies-arrayexpress

Biopsy proteome-based classification of T-cell-mediated kidney allograft rejection

T cell-mediated rejection (TCMR) remains a challenge in kidney transplantation. Based on a histopathological biopsy examination, patients can be classified into groups defining their kidney’s status, i.e. no rejection (NR), borderline rejection (BR) and acute rejection (AR). Yet, this classification...

ORGANISM(S): Homo sapiens (Human)

2025-10-27 | PXD064523 | Pride

Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection

PRJNA1200092 | ENA

Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection

PRJNA1200104 | ENA

Molecular T-cell mediated rejection in transbronchial and mucosal lung transplant biopsies

PRJNA631267 | ENA

Dynamic JAK-STAT/IFN-signaling in subclinical to clinical T cell-mediated rejection following liver transplantation

PRJNA1242403 | ENA

ALLoreactive T-Cell receptOr RePertoire in kidnEy tranSplantation

A prospective study for investigating the T-cell receptor (TCR) repertoire in T-cell mediated rejection (TCMR) after kidney transplantation. The pre-formed donor-reactive TCR repertoire was tracked in blood and tissue of patients after kidney transplantation and characteristics of TCR repertoires fr...

EGAS00001005299 | EGA

Gene expression-based, chronic active T cell-mediated rejection (CA TCMR)

PRJNA704388 | ENA

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