Sort   by:  
 Page size 
TranscriptomicsTHP1 derived macrophage and foam cell gene expression in presence and absence of T0901317 and RNAi analyses of LXRa/b
To assess the LXRa dependent regulatory pathways in macrophages and foam cells we treated our two, THP1 derived native and LXR-knockdown cell models either with T0901317 or vehicle control (DMSO).
ORGANISM(S): Homo sapiens 
2013-02-15 | E-MTAB-1106 | biostudies-arrayexpress
TranscriptomicsEffect of T0901317, AM580 or T0901317+AM580 on monocyte gene expression
The aim of this study was to investigate the effect of T0901317 LXR agonist on Retinoic Acid Receptor (RAR) family gene expression. T0901317 alone increase RARalpha gene expression in monocytes and the effects of the co treatment of the cells with T0901317 and a specific RARalpha agonist (AM580) wer...
ORGANISM(S): Homo sapiens 
2010-04-08 | E-GEOD-13407 | biostudies-arrayexpress
TranscriptomicsEffect of T0901317, AM580 or T0901317+AM580 on monocyte gene expression
The aim of this study was to investigate the effect of T0901317 LXR agonist on Retinoic Acid Receptor (RAR) family gene expression. T0901317 alone increase RARalpha gene expression in monocytes and the effects of the co treatment of the cells with T0901317 and a specific RARalpha agonist (AM580) wer...
ORGANISM(S): Homo sapiens 
2009-10-01 | GSE13407 | GEO
UnknownHemistepsin A inhibits T0901317-induced lipogenesis in the liver.
Not available
S-EPMC7907741 | biostudies-literature
GenomicsHomo sapiens
Effect of T0901317, AM580 or T0901317+AM580 on monocyte gene expression
PRJNA109765 | ENA
GenomicsEffect of LXR agonist T0901317 on the intestinal transcriptome in mice.
Effect of LXR agonist T0901317 on the intestinal transcriptome in mice.
PRJNA433938 | ENA
TranscriptomicsTranscription profiling by array of two subpopulations of tumour-associated macrophages (TAMs) treated with DMSO or T0901317 for 24h
C57BL/6 WT male mice were subjected to subcutaneous injection of 3x10^6 3LL-R cells. 15 days after tumour injection, MHCII high TAMs and MHCII low TAMs were isolated and stimulated ex vivo with either the LXR agonist T0901317 (1 micromolar) or vehicle (DMSO) for 24h.
ORGANISM(S): Mus musculus 
2020-12-10 | E-MTAB-9707 | biostudies-arrayexpress
GenomicsRNA-seq for siNr1h2 in mouse blastoid samples and T0901317-treatment in mouse ESC and EPSC
RNA-seq for siNr1h2 in mouse blastoid samples and T0901317-treatment in mouse ESC and EPSC
PRJNA867550 | ENA
TranscriptomicsIntegrated analysis of transcript level regulation of metabolism during human adipocyte differentiation [T0901317]
Here, we have focused on studying the link between metabolic changes driven by the differentiation into mature adipocytes of a human preadipocyte cell line (SGBS) and their regulation, through a combined experimental and computational approach. By collecting data on gene expression, PPARg, CEBPa, LX...
ORGANISM(S): Homo sapiens 
2013-11-19 | E-GEOD-41577 | biostudies-arrayexpress
TranscriptomicsLiver X receptor beta is the dominant LXR subtype in skeletal muscle
Liver X receptors (LXRs) are important regulators of cholesterol, lipid and glucose metabolism and have been extensively studied in liver, macrophages and adipose tissue. However, their role in skeletal muscle is not yet fully elucidated and the functional role of each of the LXRM-NM-1 and LXRM-NM-2...
ORGANISM(S): Mus musculus 
2010-03-30 | E-GEOD-13192 | biostudies-arrayexpress
Sort   by:  
 Page size