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TranscriptomicsLymphocyte gene expression data from moderate stage HD patients and controls
Highly quantitative biomarkers of neurodegenerative disease remain an important need in the urgent quest for disease modifying therapies. For Huntington's disease (HD), a genetic test is available (trait marker), but necessary state markers are still in development. In this report, we describe a lar...
ORGANISM(S): Homo sapiens 
2007-08-15 | E-GEOD-8762 | biostudies-arrayexpress
UnknownGenetic modifiers of repeat expansion disorders.
Not available
S-EPMC10754329 | biostudies-literature
UnknownActivity or connectivity? A randomized controlled feasibility study evaluating neurofeedback training in Huntington's disease.
Not available
S-EPMC7425518 | biostudies-literature
UnknownAbnormal molecular signatures of inflammation, energy metabolism, and vesicle biology in human Huntington disease peripheral tissues.
Not available
S-EPMC9450392 | biostudies-literature
UnknownAberrant Striatal Value Representation in Huntington's Disease Gene Carriers 25 Years Before Onset.
Not available
S-EPMC8423628 | biostudies-literature
UnknownInhibition of tumour necrosis factor alpha in the R6/2 mouse model of Huntington's disease by etanercept treatment.
Not available
S-EPMC6510744 | biostudies-literature
UnknownIn vivo neutralization of the protagonist role of macrophages during the chronic inflammatory stage of Huntington's disease.
Not available
S-EPMC6065433 | biostudies-literature
UnknownHuntington disease alters the actionable information in plasma extracellular vesicles.
Not available
S-EPMC10775183 | biostudies-literature
ProteomicsDual FAN1 activities stabilize the HTT CAG repeat
Recent data strongly suggest HTT CAG repeat expansion drives Huntington’s disease (HD) pathogenesis and that disease development is modulated by components of the DNA damage response (DDR) pathway. FAN1 has been identified as a major HD modifier which slows expansion of the HTT CAG repeat in several...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD023221 | Pride
Crosslinking Fan1 
UnknownPrion-mediated neurodegeneration is associated with early impairment of the ubiquitin-proteasome system.
Not available
S-EPMC4752964 | biostudies-literature
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