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UnknownIdentification of a small TAF complex and its role in the assembly of TAF-containing complexes.
Not available
S-EPMC1820849 | biostudies-literature
TranscriptomicsChIP-chip from H9 hESCs for RNA Polymerase II, TBP, TAF3, TAF5, TAF7, and TAF11
The general transcription factor TFIID is composed of the TATA-box-binding protein (TBP) and approximately 14 TBP-associated factors (TAFs). Here we find, unexpectedly, that undifferentiated human embryonic stem cells (hESCs) contain only six TAFs (TAFs 2, 3, 5, 6, 7 and 11), whereas following diffe...
ORGANISM(S): Homo sapiens 
2012-11-19 | E-GEOD-39312 | biostudies-arrayexpress
GenomicsGenome-wide maps of TBP-associated factor (TAF, Taf1) in S.cerevisiae
The goals of this study are to compare Next-Generation-Sequecing (NGS)-derived genome-wide occupancy of TAF (Taf1) comparing with other basal initiation components (TBP and TFIIB), histones (H3, H4, Htz1 and H4 acetylation) and histone regulator complexes (Swr1, Bdf1) in S. cerevisiae.
ORGANISM(S): Saccharomyces cerevisiae 
2017-02-14 | GSE94851 | GEO
UnknownTwo novel Drosophila TAF(II)s have homology with human TAF(II)30 and are differentially regulated during development.
Not available
S-EPMC85347 | biostudies-literature
UnknownCloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1.
Not available
S-EPMC108885 | biostudies-literature
ProteomicsProteomic Mapping of multifunctional complexes in triatomine Saliva
Salivary multiprotein complexes from Triatoma infestans, Triatoma dimidiata, Dipetalogaster maxima, Rhodnius prolixus, and Rhodnius neglectus were identified by Blue-Native-PAGE (BN-PAGE) coupled with liquid chromatography tandem mass spectrometry.
ORGANISM(S): Triatominae (ncbitaxon:70999) 
2020-03-18 | MSV000085118 | MassIVE
GenomicsPCGF Homologs and RYBP Define Functionally Distinct PRC1 Family Complexes
The heterogeneous nature of mammalian PRC1 complexes has hindered our understanding of their biological functions. Here, we present a comprehensive proteomic and genomic analysis that uncovered six major groups of PRC1 complexes each containing a distinct PCGF subunit, a RING1A/B ubiquitin ligase, a...
ORGANISM(S): Homo sapiens 
2012-02-09 | E-GEOD-34774 | biostudies-arrayexpress
GenomicsH2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation
Chromatin modifications have been implicated in the self-renewal and differentiation of embryonic stem cells (ESCs). However, the function of histone variant H2A.Z in ESCs remains unclear. We show that H2A.Z is highly enriched at promoters and enhancers and is required for both efficient self-renewa...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-34483 | biostudies-arrayexpress
GenomicsSS18-SSX-mediated hijacking of BAF complexes drives synovial sarcoma
Synovial sarcoma (SS) is defined by a recurrent t(x;18) chromosomal translocation, which produces the hallmark SS18-SSX oncogenic fusion. Incorporation of SS18-SSX into BAF complexes renders BAF complexes aberrant in two distinct manners: the addition of 78aa of SSX onto SS18, and concomitant loss o...
EGAS00001002920 | EGA
UnknownPP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ.
Not available
S-EPMC9293736 | biostudies-literature
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