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Jmjd3 is trimethyl H3K27 specific demethylase required for M2 macrophage polarization. Genomic fragments obtained from wild-type and Jmjd3-/- mouse macrophages were immunoprecipitated with anti H3K27me3 Ab, and deep sequencing was performed. wild-type and Jmjd3-/- macrophages
ORGANISM(S): Mus musculus 
In this study, we exploited interactome-based approach to isolate Regnase-1 protein complexes and found that TLR-ligand, IL-1β, or IL-17 stimulation induces formation of the Regnase-1-14-3-3 or -βTRCP complex in a mutually exclusive manner.
ORGANISM(S): Homo Sapiens (human) 
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