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MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
TranscriptomicsInduced Sputum Genes Associated With Spirometroc and Radiological Disease Severity in COPD Ex-smokers
Induced sputum is used to sample inflammatory cells, predominantly neutrophils and macrophages, from the airways of COPD patients. Our aim was to identify candidate genes associated with the degree of airflow obstruction and the extent of emphysema by expression profiling, and then to confirm these ...
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-22148 | biostudies-arrayexpress
MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Murine UPLC-MS/MS assays)

Progressive lung function decline is a hallmark of chronic obstructive pulmonary disease (COPD). Airway dysbiosis occurs in COPD, but whether it contributes to disease progression remains unknown. Here we showed, through a longitudinal analysis on two cohorts involving four UK centers, that basel...

2023-06-12 | MTBLS6894 | MetaboLights
TranscriptomicsAltered gene expression in blood and sputum from COPD patients with frequent exacerbations
Investigation of gene expression profiles among patients with COPD frequent exacerbations and to find gene targets as predictors of exacerbations COPD patient samples analysed by microarray, followed by PCR testing to identify gene predictors
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-54837 | biostudies-arrayexpress
UnknownModified Juvenile Spondyloarthritis Disease Activity Index in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry.
Not available
S-EPMC10066819 | biostudies-literature
UnknownImplementation study of the CARRA Uveitis Consensus Treatment Plans: feasibility for clinical practice and applicability for research.
Not available
S-EPMC11457454 | biostudies-literature
UnknownRacial Disparities and Achievement of the Low Lupus Disease Activity State: A CARRA Registry Study.
Not available
S-EPMC11684980 | biostudies-literature
UnknownComparative Effectiveness of a Second Tumor Necrosis Factor Inhibitor Versus a Non-Tumor Necrosis Factor Biologic in the Treatment of Patients With Polyarticular-Course Juvenile Idiopathic Arthritis.
Not available
S-EPMC11288784 | biostudies-literature
UnknownInterleukin (IL)-1/IL-6-Inhibitor-Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses.
Not available
S-EPMC11560592 | biostudies-literature
UnknownLong-term safety of canakinumab in patients with systemic juvenile idiopathic arthritis: 5-year results from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry.
Not available
S-EPMC12538899 | biostudies-literature
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