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TranscriptomicsGenome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila
Polycomb group (PcG) proteins maintain transcriptional repression of developmentally important genes and have been implicated in cell proliferation and stem-cell self-renewal. We used a genome-wide approach to map binding patterns of PcG proteins (Pc, esc and Sce) in Drosophila Kc cells. We found th...
ORGANISM(S): Drosophila melanogaster 
2010-06-11 | E-GEOD-4564 | biostudies-arrayexpress
TranscriptomicsProtein profiling reveals five principal chromatin types in Drosophila cells
The local protein composition of chromatin is important for the regulation of transcription and other functions. By integrative analysis of genome-wide binding maps of 53 broadly selected chromatin components in Drosophila cells, we show that the genome is segmented into five principal chromatin typ...
ORGANISM(S): Drosophila melanogaster 
2010-10-01 | E-GEOD-22069 | biostudies-arrayexpress
TranscriptomicsA network model of the molecular organization of chromatin in Drosophila
Chromatin governs gene regulation and genome maintenance, yet a substantial fraction of the chromatin proteome is still unexplored. Moreover, a global model of the chromatin protein network is lacking. By screening >100 candidates we identify 42 Drosophila proteins that were not previously associate...
ORGANISM(S): Drosophila melanogaster 
2013-02-12 | E-GEOD-36175 | biostudies-arrayexpress
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