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ProteomicsIn vitro phosphorylation of trypsin-digested K562 cell lysate by TAM family kinases
K562 cell lysate was digested with trypsin, dephosphorylated with lambda phosphatase, and treated in an in vitro kinase reaction with Axl, Mer or Tyro3 kinase, alongside a control reaction for each that contained no kinase. Samples were phosphoenriched with the SMOAC approach (TiO2 and FeNTA) and an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-29 | MSV000092784 | MassIVE
TranscriptomicsComparison of Invasive TAM sub-population to General TAM population
The tumor microenvironment modifies the malignancy of tumors. In solid tumors this environment is populated by many macrophages (tumor-associated macrophages; TAMs) that in genetic studies that depleted these cells from mouse models of breast cancer were shown to promote tumor progression to maligna...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-18295 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression during tumor-associated macrophage (TAM) differentiation
To further analyze the change of microRNA(miRNA) between normal peritoneal macrophage(PEC) and TAM from early tumor(12 days after 4T1 cell injection) or TAM from late tumor(21 days after 4T1 cell injection) , we employed Agilent mouse microRNA microarray Rel 12.0 as a discovery platform to identify ...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-67408 | biostudies-arrayexpress
TranscriptomicsMultiplexed DNA high throughput genotyping study to determine the mutational status of transient (TAM) and acute myeloid leukaemic (ML-DS) Down syndrome individuals.
We used a 48.48 Fluidigm Access Array approach (1070 Amplicons spanning 62 genes: 157kB coverage) of genomic DNA from over 100 samples to genotype individuals with transient abnormal myelopoiesis (TAM) and acute myeloid leukemia of Down syndrome (ML-DS). Individually barcoded patient samples were ...
ORGANISM(S): Homo sapiens 
2019-07-17 | E-MTAB-7729 | biostudies-arrayexpress
TranscriptomicsExpression data from wheat cultivar TAM 107 flag leaf
We used microarray to study the transcriptome response of wheat flag leaves to heat stress (40℃) In order to study the transcriptome response of wheat flag leaf to heat stress, wheat cultivar ‘TAM 107’ plants were subjected to heat stress (40℃). After 1 hour of stress, flag leaves were sampled from ...
ORGANISM(S): Triticum aestivum 
2015-08-13 | E-GEOD-60351 | biostudies-arrayexpress
TranscriptomicsTamoxifen induces expression of immune-response related genes in cultured NHMEC
Administration of tamoxifen (TAM) as breast cancer adjuvant therapy is associated with a 50% reduction in breast cancer risk and an increase in endometrial cancer risk. To investigate underlying mechanisms, we documented TAM-induced gene expression changes in cultured normal human mammary epithelial...
ORGANISM(S): Homo sapiens 
2009-01-29 | E-GEOD-13476 | biostudies-arrayexpress
GenomicsRNA-seq Analysis Reveals Different Drought Tolerance Mechanisms in Two Broadly Adapted Wheat Cultivars ‘TAM 111’ and ‘TAM 112’
RNA-seq Analysis Reveals Different Drought Tolerance Mechanisms in Two Broadly Adapted Wheat Cultivars ‘TAM 111’ and ‘TAM 112’
PRJNA659916 | ENA
GenomicsEvolution of TAM gene expression in ID8 tumors
Evolution of TAM gene expression in ID8 tumors
PRJNA521020 | ENA
TranscriptomicsExpression data from mouse aorta during and following transient hyperglycaemia
Immediate and early effects of transient hyperglycaemia were examined using fully- reversible transgenic diabetic mice. Transient hyperglycaemia altered expression of 769 arterial genes, of which 200 did not reverse following recovery from hyperglycaemia. Many such genes are known to promote athero...
ORGANISM(S): Mus musculus 
2010-08-09 | E-GEOD-15401 | biostudies-arrayexpress
TranscriptomicsComparative in situ gene expression profile of starry-sky tumor-associated macrophages and germinal centre macrophages
Cells undergoing apoptosis are known to modulate their tissue microenvironments. By acting on phagocytes, notably macrophages, apoptotic cells inhibit immunological and inflammatory responses and promote trophic signaling pathways. Paradoxically because of their potential to cause death of tumor cel...
ORGANISM(S): Mus musculus 
2014-12-20 | E-GEOD-64366 | biostudies-arrayexpress
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