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TranscriptomicsTranscription profiling of E. coli K12 luxS-dependent gene regulation
The bacterial quorum-sensing autoinducer 2 (AI-2) has received intense interest because the gene for its synthase, luxS, is common among a large number of bacterial species. We have identified luxS-controlled genes in Escherichia coli under two different growth conditions using DNA microarrays. Twen...
ORGANISM(S): Escherichia coli 
2008-06-16 | E-GEOD-9582 | biostudies-arrayexpress
ProteomicsDependency of NELF-E-KAT2B epigenetic axis in breast cancer carcinogenesis
Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Here, we identified the transcriptional complex, NELF (Negative elongation factor), as an important regulator of this process. Using cancer cell lines and patient-derived tumor organoids, we demonstrated th...
ORGANISM(S): Homo Sapiens (human) 
2023-01-28 | PXD031304 | JPOST Repository
TranscriptomicsTranscription profiling of E.coli luxS mutants vs. W3110 wild type
The bacterial quorum-sensing autoinducer 2 (AI-2) has received intense interest because the gene for its synthase, luxS, is common among a large number of bacterial species. We have identified luxS-controlled genes in Escherichia coli under two different growth conditions using DNA microarrays. Twen...
ORGANISM(S): Escherichia coli 
2008-06-16 | E-GEOD-9587 | biostudies-arrayexpress
ProteomicsIn vitro phosphorylation of trypsin-digested K562 cell lysate by TAM family kinases
K562 cell lysate was digested with trypsin, dephosphorylated with lambda phosphatase, and treated in an in vitro kinase reaction with Axl, Mer or Tyro3 kinase, alongside a control reaction for each that contained no kinase. Samples were phosphoenriched with the SMOAC approach (TiO2 and FeNTA) and an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-29 | MSV000092784 | MassIVE
TranscriptomicsTamoxifen induces expression of immune-response related genes in cultured NHMEC
Administration of tamoxifen (TAM) as breast cancer adjuvant therapy is associated with a 50% reduction in breast cancer risk and an increase in endometrial cancer risk. To investigate underlying mechanisms, we documented TAM-induced gene expression changes in cultured normal human mammary epithelial...
ORGANISM(S): Homo sapiens 
2009-01-29 | E-GEOD-13476 | biostudies-arrayexpress
TranscriptomicsComparison of Invasive TAM sub-population to General TAM population
The tumor microenvironment modifies the malignancy of tumors. In solid tumors this environment is populated by many macrophages (tumor-associated macrophages; TAMs) that in genetic studies that depleted these cells from mouse models of breast cancer were shown to promote tumor progression to maligna...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-18295 | biostudies-arrayexpress
UnknownResponses to Real-World and Hypothetical E-Cigarette Flavor Bans Among US Young Adults Who Use Flavored E-Cigarettes.
Not available
S-EPMC11260892 | biostudies-literature
TranscriptomicsMultiplexed DNA high throughput genotyping study to determine the mutational status of transient (TAM) and acute myeloid leukaemic (ML-DS) Down syndrome individuals.
We used a 48.48 Fluidigm Access Array approach (1070 Amplicons spanning 62 genes: 157kB coverage) of genomic DNA from over 100 samples to genotype individuals with transient abnormal myelopoiesis (TAM) and acute myeloid leukemia of Down syndrome (ML-DS). Individually barcoded patient samples were ...
ORGANISM(S): Homo sapiens 
2019-07-17 | E-MTAB-7729 | biostudies-arrayexpress
TranscriptomicsExpression data from wheat cultivar TAM 107 flag leaf
We used microarray to study the transcriptome response of wheat flag leaves to heat stress (40℃) In order to study the transcriptome response of wheat flag leaf to heat stress, wheat cultivar ‘TAM 107’ plants were subjected to heat stress (40℃). After 1 hour of stress, flag leaves were sampled from ...
ORGANISM(S): Triticum aestivum 
2015-08-13 | E-GEOD-60351 | biostudies-arrayexpress
TranscriptomicsHigh-density gene expression analysis of tumor-associated macrophages from mouse mammary tumors
Clinical and experimental evidence indicates that tumor-associated macrophages (TAMs) promote malignant progression. In breast cancer, TAMs enhance tumor angiogenesis, tumor cell invasion, matrix remodeling, and immune suppression against the tumor. In this study, we examined late-stage mammary tumo...
ORGANISM(S): Mus musculus 
2010-06-21 | E-GEOD-18404 | biostudies-arrayexpress
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