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ProteomicsIn vitro phosphorylation of trypsin-digested K562 cell lysate by TAM family kinases
K562 cell lysate was digested with trypsin, dephosphorylated with lambda phosphatase, and treated in an in vitro kinase reaction with Axl, Mer or Tyro3 kinase, alongside a control reaction for each that contained no kinase. Samples were phosphoenriched with the SMOAC approach (TiO2 and FeNTA) and an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-29 | MSV000092784 | MassIVE
TranscriptomicsFish oil alters tamoxifen-modulated expression of genes related to differentiation, proliferation, metastasis, and immune response in rat mammary tumors
Herein, we evidence that tamoxifen treatment modifies gene expression of mammary tumors depending upon the type of dietary fat fed to the animals. Rats initiated with MNU and treated with tam were fed a diet rich in corn oil (CO) or fish oil (FO). After 8 weeks, tumors of the same histological type ...
ORGANISM(S): Rattus norvegicus 
2012-10-16 | E-GEOD-27465 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E.coli luxS mutants vs. W3110 wild type
The bacterial quorum-sensing autoinducer 2 (AI-2) has received intense interest because the gene for its synthase, luxS, is common among a large number of bacterial species. We have identified luxS-controlled genes in Escherichia coli under two different growth conditions using DNA microarrays. Twen...
ORGANISM(S): Escherichia coli 
2008-06-16 | E-GEOD-9587 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli K12 luxS-dependent gene regulation
The bacterial quorum-sensing autoinducer 2 (AI-2) has received intense interest because the gene for its synthase, luxS, is common among a large number of bacterial species. We have identified luxS-controlled genes in Escherichia coli under two different growth conditions using DNA microarrays. Twen...
ORGANISM(S): Escherichia coli 
2008-06-16 | E-GEOD-9582 | biostudies-arrayexpress
TranscriptomicsCXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AHR signaling
Targeting the estrogen signaling pathway has proved to be of great value in the treatment of human breast cancer. Tamoxifen, a selective estrogen receptor modulator (SERM), is the most widely used antiestrogen. However, only 40-50% of patients with estrogen receptor (ER) positive breast cancer benef...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-31831 | biostudies-arrayexpress
UnknownThe BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC5065110 | biostudies-literature
UnknownA microarray-based high throughput molecular marker genotyping method: the tagged microarray marker (TAM) approach.
Not available
S-EPMC206481 | biostudies-literature
ProteomicsExtracellular matrix educates a tumor macrophage phenotype found in ovarian cancer metastasis
Recent studies have shown the tumor extracellular matrix (ECM) associates with immunosuppression, and that targeting the ECM can improve immune infiltration and immunotherapy response. A question that remains is whether the ECM is directly educating the immune phenotypes seen in cancer. We identifie...
ORGANISM(S): Homo sapiens (Human) 
2023-04-11 | PXD036940 | Pride
Cancer Tumor-associated macrophages Proteomics Decellularized tissue model Immunity Extracellular matrix Lc-ms/ms 
UnknownPolyamine Blocking Therapy Decreases Survival of Tumor-Infiltrating Immunosuppressive Myeloid Cells and Enhances the Antitumor Efficacy of PD-1 Blockade.
Not available
S-EPMC7541445 | biostudies-literature
UnknownExtracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis.
Not available
S-EPMC10185550 | biostudies-literature
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