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TranscriptomicsA sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
Myc is an oncogenic transcription factor frequently dysregulated in human cancer. To identify pathways supporting the Myc oncogenic program, we employed a genome-wide RNAi screen for Myc-synthetic-lethal (MySL) genes and uncovered a role for the SUMO-activating-enzyme (SAE1/2). Loss of SAE1/2 enzyma...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-34055 | biostudies-arrayexpress
GenomicsEGAD00000000114
Whole transcriptome sequence data from 18 ovarian clear-cell carcinoma samples and one TOV21G ovarian clear-cell carcinoma cell line
EGAD00000000114 | EGA
GenomicsARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
We have sequenced the whole transcriptomes of 18 ovarian clear-cell carcinomas and 1 ovarian clear-cell carcinoma cell line and found somatic mutations in ARID1A (the AT-rich interactive domain 1A [SWI-like] gene) in 6 of the samples. ARID1A encodes BAF250a, a key component of the SWI–SNF chromati...
EGAS00000000075 | EGA
UnknownThe landscape of viral associations in human cancers.
Not available
S-EPMC8076016 | biostudies-literature
UnknownIntegrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.
Not available
S-EPMC5964983 | biostudies-literature
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
Not available
S-EPMC11629703 | biostudies-literature
UnknownCanadian Surgery Forum.
Not available
S-EPMC3432251 | biostudies-literature
UnknownLaparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
Not available
S-EPMC6061087 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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