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ProteomicsProteomics, post-translational modifications, and integrative analyses reveal heterogeneity of molecular mechanisms within medulloblastoma subgroups
Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Francois JP, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA,...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-07-20 | MSV000082644 | MassIVE
TranscriptomicsTranscription profiling of immortalized human lung epithelial cells following oncogenic KRAS expression and TBK1 suppression
The purpose of the dataset is to analyze expression of genes induced by KRAS and regulated by TBK1; The proto-oncogene KRAS is mutated in a wide array of human cancers, most of which are aggressive and respond poorly to standard therapies. Although the identification of specific oncogenes has led to...
ORGANISM(S): Homo sapiens 
2009-11-15 | E-GEOD-17643 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human immortalized lung epithelial cells following infection with oncogenic KRAS (G12V)
The purpose of the dataset is to analyze expression of genes induced by KRAS; The proto-oncogene KRAS is mutated in a wide array of human cancers, most of which are aggressive and respond poorly to standard therapies. Although the identification of specific oncogenes has led to the development of cl...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-17671 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lung epithelial cells ollowing oncogenic KRAS expression and TBK1 suppression or infection with oncogenic KRAS (G12V) - SuperSeries
The proto-oncogene KRAS is mutated in a wide array of human cancers, most of which are aggressive and respond poorly to standard therapies. Although the identification of specific oncogenes has led to the development of clinically effective, molecularly targeted therapies in some cases, KRAS has rem...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-17672 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human skeletal muscle from males with type 2 diabetes to identify genes involved in oxidative phosphorylation
DNA microarrays can be used to discover gene expression changes characteristic of human disease. This is challenging, however, when relevant differences are subtle at the level of individual genes. We introduce an analytical strategy, Gene Set Enrichment Analysis, designed to detect modest but coord...
ORGANISM(S): Homo sapiens 
2007-07-17 | E-CBIL-30 | biostudies-arrayexpress
TranscriptomicsMYC regulation of a "poor prognosis" metastatic cancer cell state
This SuperSeries is composed of the following subset Series: GSE14987: Expression data from ERBB2 over-expression and EGF stimulation in MCF10A cells GSE14988: Expression data from DHT stimulation vs. control in LNCaP cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-14990 | biostudies-arrayexpress
GenomicsGenomic Sequencing of Medulloblastoma

Medulloblastomas are the most common malignant brain tumors in children. Identifying and understanding the genetic events that drive these tumors is critical for the development of more effective diagnostic, prognostic and therapeutic strategies. Recently, our group and others described distinct ...

phs000504.v1.p1 | EGA
ProteomicsMudPIT analysis of STRN4 interacting proteins from HEK TER cells expressing either SV40 ST or GFP
HEK TER cells expressing either SV40 ST or GFP (30 x 15-cm diameter plates) were harvested with lysis buffer (20 mM imidazole HCl, 2 mM EDTA, 2 mM EGTA, pH 7.0 with 10 ug/mL each of aprotinin, leupeptin, pepstatin, 1 mM benzamidine, and 1 mM PMSF). The clarified cell extract was incubated overnight ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-12-05 | MSV000084662 | MassIVE
UnknownDeclaracion consenso de la Asociacion Colombiana de Medicina Critica y Cuidados Intensivos (AMCI) para atencion y manejo del paciente pediatrico con sospecha o confirmacion de infeccion severa por SARS-CoV-2 Consensus statement of the Colombian Association of Critical Medicine and Intensive Care (AMCI) for the care and management of the paediatric patient with suspicion or confirmation of severe infection by SARS-CoV-2
Not available
S-EPMC7538131 | biostudies-literature
Unknown[18F]DCFPyL PET/CT versus [18F]fluoromethylcholine PET/CT in Biochemical Recurrence of Prostate Cancer (PYTHON): a prospective, open label, cross-over, comparative study.
Not available
S-EPMC10542307 | biostudies-literature
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