Tamborero David D

Chronic lymphocytic leukemia (CLL) is a B-cell neoplasm with a heterogeneous clinical and biological behavior. We have performed deep RNA sequencing in different subpopulations of B-lymphocytes from healthy individuals and CLL cells from a cohort of 98 patients, and characterized the CLL transcript...

EGAS00001000374 | EGA

ena-DATASET-Hospital Clinic Barcelona-12-08-2015-11:33:40:243-146 - samples

Exome Sequencing. 3 ÃŽÂ¼g of genomic DNA from each sample were sheared and used for the construction of a paired-end sequencing library as described in the paired-end sequencing sample preparation protocol provided by Illumina41. Enrichment of exonic sequences was then performed for each library usi...

EGAD00001001464 | EGA

ena-DATASET-Hospital Clinic Barcelona-21-07-2015-12:09:53:274-78 - samples

RNASeq sequencing. Each library was sequenced using TruSeq SBS Kit v3-HS, in paired-end mode with a read length of 2 ÃƒÂ— 76 bp. We generated more than 20 million paired-end reads for each sample in a fraction of a sequencing lane on HiSeq2000 (Illumina Inc.) following the manufacturerÃ¢Â€Â™s protoc...

EGAD00001001443 | EGA

ena-DATASET-Hospital Clinic Barcelona-13-08-2015-12:02:30:199-229 - samples

Whole Genome sequencing. 2 ÃŽÂ¼g of genomic DNA from each sample was used for the construction of two short-insert paired-end sequencing libraries. Both types of libraries were sequenced in paired-end mode on Illumina GAIIx (2 ÃƒÂ— 151 bp) using Sequencing kit v4 or Illumina HiSeq2000 (2x101 bp) usi...

EGAD00001001466 | EGA

U219-array-CLL-EGAS00001001306

CLL Expression Array

EGAD00010000875 | EGA

Integrated Genomic Analysis of Chronic Lymphocytic Leukaemia

Chronic lymphocytic leukaemia (CLL) is a frequent and heterogeneous disease whose genetic alterations determining the clinicobiological behaviour are not fully understood. Here, we describe a comprehensive evaluation of the genomic landscape of 452 CLLs and 54 monoclonal B-lymphocytosis (MBL), a pre...

EGAS00001001306 | EGA