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MetabolomicsRumen Fluid Metabolomic Profiles of Postpartum Tan Ewes Fed Diets with Different Nutrient Levels
This study investigated the rumen fluid metabolomic profiles of postpartum Tan ewes fed diets formulated to meet 100%, 115%, or 130% of nutrient requirements. Rumen fluid samples were collected from six ewes per dietary group at each ewe’s individual first estrus.
2026-07-21 | MTBLS15108 | MetaboLights
MetabolomicsRumen Fluid Metabolomic Profiles of Postpartum Tan Ewes Fed Diets with Different Nutrient Levels
This study investigated the rumen fluid metabolomic profiles of postpartum Tan ewes fed diets formulated to meet 100%, 115%, or 130% of nutrient requirements. Rumen fluid samples were collected from six ewes per dietary group at each ewe’s individual first estrus.
2026-07-21 | MTBLS15107 | MetaboLights
MetabolomicsEffects of Different Nutritional Levels of Diets on Serum Metabolomics Profiles in Postpartum Tan Sheep
This study investigated the metabolomic characteristics of rumen fluid in postpartum New Zealand ewes after they were fed diets that met 100%, 115% or 130% of their nutritional requirements. Six ewes in each group collected individual blood samples at the time of their first estrus.
2026-07-25 | MTBLS15146 | MetaboLights
MetabolomicsDysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model

Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multi-drug resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to control infection including zinc stres...

2022-02-23 | MTBLS318 | MetaboLights
ProteomicsTTC33 forms a complex with WDR61 and PHF5A to recruit factors relevant to genomic integrity 2/2
The functions of many human proteins remain unknown, highlighting major gaps in our understanding of cellular biology. TTC33 is an evolutionarily conserved tetratricopeptide repeat (TPR) protein expressed across human tissues, whose molecular role is not defined. Here we identify the TTC33 partners ...
ORGANISM(S): Homo sapiens (Human) 
2026-07-13 | PXD043138 | Pride
Phf5a and ttc33 form a vertebrate-specific novel complex coined ttc33-associated network (tan) which together with ccdc97 regulate levels of mrnas that mediate neurotransmitter release Wdr61 
MetabolomicsDeep functional analysis of synII, a 770 kb synthetic yeast chromosome
Here we report the design, construction and characterization of a 770 Kb synthetic yeast chromosome II (synII). With the UPLC-MS method, we demonstrated synII maintains a nearly wild-type phenotype and fitness despite hundreds of designer editing to it. Our phenomics, transcriptomics, proteomics dat...
2016-10-13 | MTBLS296 | MetaboLights
MetabolomicsImidazole ketone erastin induces ferroptosis and slows tumor growth in a mouse lymphoma model
Ferroptosis is a form of regulated cell death that can be induced by inhibition of the cystine-glutamate antiporter, system xc-. Among the existing system xc- inhibitors, imidazole ketone erastin (IKE) is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially s...
2019-04-17 | MTBLS774 | MetaboLights
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
MetabolomicsCharacterization of white tea metabolome: comparison against green and black tea by a nontargeted metabolomics approach
White tea is considered the least processed form of tea and is reported to have a series of potent bioactivities, such as antioxidant, anti-inflammatory, anti-mutagenic, and anti-cancer activities. However, the chemical composition of white tea and the dynamic changes of the metabolites during the m...
2017-03-23 | MTBLS403 | MetaboLights
GenomicsA novel TYRP1 variant is associated with liver and tan coat colour in Lancashire Heelers
A novel TYRP1 variant is associated with liver and tan coat colour in Lancashire Heelers
PRJEB32213 | ENA
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