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TranscriptomicsTranscription profiling by array of human pancreatic tumours in xenografts to investigate the antitumor activity and molecular effects of the novel Hsp 90 Inhibitor, IPI-504, in pancreatic cancer
Tumors from pancreatic cancer specimens obtained at surgery were used for efficacy testing and biologic analysis. These tumors were s.c. explanted in xenograft models for subsequent treatment experiments. This study aimed to assess the antitumor activity of the Hsp90 inhibitor, IPI-504, in pancreat...
ORGANISM(S): Homo sapiens 
2009-08-07 | E-GEOD-12113 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pancreatic cancer samples: coordinated over-expression of genes in the EGFR pathway predicts sensitivity to EGFR inhibition
Tumors from pancreatic cancer specimens obtained at surgery were used for efficacy testing and biologic analysis Experiment Overall Design: Eighteen tumor samples were profiled in duplicates. Ten samples were used in the training set and eight samples were used as the validation set.
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9599 | biostudies-arrayexpress
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