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TranscriptomicsTranscription profiling of human TLR2/1 stimulated human monocytes with the Mycobacterium tuberculosis derived 19kDa lipopeptide reveals Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
In innate immune responses, activation of Toll-like receptors (TLRs) triggers direct antimicrobial activity against intracellular bacteria, which in murine, but not human, monocytes and macrophages is mediated principally by nitric oxide. We report here that TLR activation of human macrophages up-re...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-8921 | biostudies-arrayexpress
TranscriptomicsGlobal gene profiling comparison between hydrogen sulfide- and N-methyl-D-aspartate-induced neuronal deaths
Hydrogen sulfide (H2S), present in abundance in the mammalian brain, has recently been demonstrated to induce a dose- and time-dependent apoptotic-necrotic continuum in murine primary cortical neurons, which was successfully attenuated upon application of N-methyl-D-aspartate (NMDA) receptor antagon...
ORGANISM(S): Mus musculus 
2013-01-23 | E-GEOD-16035 | biostudies-arrayexpress
UnknownLittle effect of the tan locus on pigmentation in female hybrids between Drosophila santomea and D. melanogaster.
Not available
S-EPMC2798109 | biostudies-literature
TranscriptomicsTranscription profiling of mouse white adipose tissue from PPARb/d knockout
Analysis of white adipose tissue of PPARb/d knockout mice. Data may point towards putative target genes of PPARb/d and thus the function of PPARb/d in white adipose tissue. Datasets were used to identify glycogen synthase 2 as novel PPAR target. Experiment Overall Design: Three month old male PPARb/...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8344 | biostudies-arrayexpress
TranscriptomicsTan SingleCell
Transcriptional profiling was performed on 18 cells isolated from libraries produced by culture of cells extracted from neonatal foreskin. The profiling was exploratory in nature, with no pre-defined sample phenotypes except for origin of the cells. Post-hybridization, the single-cell libraries were...
ORGANISM(S): Homo sapiens 
2013-02-18 | E-MTAB-824 | biostudies-arrayexpress
UnknownRelationship between rumen microbial differences and traits among Hu sheep, Tan sheep, and Dorper sheep.
Not available
S-EPMC9492252 | biostudies-literature
UnknownSunbeds with UVB radiation can produce physiological levels of serum 25-Hydroxyvitamin D in healthy volunteers.
Not available
S-EPMC5821157 | biostudies-literature
TranscriptomicsTranscriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils
The role of myeloid cells in supporting cancer growth is well established. Most work has focused on myeloid-derived suppressor cells (MDSC) that accumulate in tumor-bearing animals, but tumor-associated neutrophils (TAN) are also known to be capable of augmenting tumor growth. However, little is kno...
ORGANISM(S): Mus musculus 
2013-01-04 | E-GEOD-43254 | biostudies-arrayexpress
UnknownThe Engineering, Expression, and Immobilization of Epimerases for D-allulose Production.
Not available
S-EPMC10454905 | biostudies-literature
ProteomicsTTC33 forms a complex with WDR61 and PHF5A to recruit factors relevant to genomic integrity 2/2
The functions of many human proteins remain unknown, highlighting major gaps in our understanding of cellular biology. TTC33 is an evolutionarily conserved tetratricopeptide repeat (TPR) protein expressed across human tissues, whose molecular role is not defined. Here we identify the TTC33 partners ...
ORGANISM(S): Homo sapiens (Human) 
2026-07-13 | PXD043138 | Pride
Phf5a and ttc33 form a vertebrate-specific novel complex coined ttc33-associated network (tan) which together with ccdc97 regulate levels of mrnas that mediate neurotransmitter release Wdr61 
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