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UnknownLiang-Ge-San: a classic traditional Chinese medicine formula, attenuates acute inflammation via targeting GSK3β.
Not available
S-EPMC10338930 | biostudies-literature
UnknownDiptoindonesin G promotes ERK-mediated nuclear translocation of p-STAT1 (Ser727) and cell differentiation in AML cells.
Not available
S-EPMC5520695 | biostudies-literature
ProteomicsSystemic metabolic alterations correlate with islet-level prostaglandin E2 production and signaling mechanisms that predict beta-cell dysfunction in a mouse model of type 2 diabetes
The transition from β-cell compensation to β-cell failure is not well understood. Previous works by our group and others have demonstrated a role for Prostaglandin EP3 receptor (EP3), encoded by the Ptger3 gene, in the loss of functional β-cell mass in T2D. The primary endogenous EP3 ligand is the a...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD022624 | Pride
Prostaglandin e2  gut microbiota  metabolomics  adipokines  incretins  insulin secretion 
UnknownConstitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation.
Not available
S-EPMC8568893 | biostudies-literature
ProteomicsIntegrated proteome and malonylome analyses reveal the potential meaning of TLN1 and ACTB in end-stage renal disease
Purpose: End-stage renal disease (ESRD) is a condition that is characterized by the loss of kidney function. ESRD patients suffer from various endothelial dysfunctions, inflammation, and immune system defects. Lysine malonylation (Kmal) is a recently discovered post-translational modification (PTM)....
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035147 | Pride
Lysine malonylation (kmal) Platelet activation Post-translational modification (ptm) End-stage renal disease (esrd) Chronic kidney disease (ckd) 
UnknownCombined effects of TGFB1 +869 T/C and +915 G/C polymorphisms on acute rejection risk in solid organ transplant recipients: a systematic review and meta-analysis.
Not available
S-EPMC3976347 | biostudies-literature
UnknownZrOx Negative Capacitance Field-Effect Transistor with Sub-60 Subthreshold Swing Behavior.
Not available
S-EPMC7855158 | biostudies-literature
TranscriptomicsRunx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells
The transcription factor RUNX1 is frequently mutated in myelodysplastic syndrome and leukemia. RUNX1 mutations can be early events, creating pre-leukemic stem cells that expand in the bone marrow. Here we show that, counter-intuitively, Runx1 deficient hematopoietic stem and progenitor cells (HSPCs)...
ORGANISM(S): Mus musculus 
2015-07-27 | E-GEOD-67609 | biostudies-arrayexpress
Unknown<i>Ardisia japonica</i> (Thunb.) Blume and <i>Lespedeza cuneata</i> G. Don may treat chronic obstructive pulmonary disease by targeting HK2 and PTAFR.
Not available
S-EPMC12090870 | biostudies-literature
UnknownIdentification of Chromosome Segment Substitution Lines of Gossypium barbadense Introgressed in G. hirsutum and Quantitative Trait Locus Mapping for Fiber Quality and Yield Traits.
Not available
S-EPMC5014324 | biostudies-literature
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