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TranscriptomicsGenome wide profiling of Su(H) [CSL] binding in Drosophila melanogaster larval CNSs where Notch is hyperactive in neuroblasts for 24 hours
The Notch pathway is a well conserved cell to cell communication mechanism that is normally involved in many developmental processes and when aberrantly activated it leads to diseases such as cancer. One such example is the neural stem cell tumours that arise from constitutive Notch activity in Dros...
ORGANISM(S): Drosophila melanogaster 
2015-12-15 | E-GEOD-68614 | biostudies-arrayexpress
TranscriptomicsGene profiles induced by overexpression of wild-type and mutant Notch1 variants in MCF10A mammary epithelial cell line
Expression of a constitutively active Notch-1 intracellular domain (NICD) in MCF-10A cells was found to induce two distinct types of 3D structures: large, hyperproliferative structures and small, growth-arrested structures with reduced cell-to-matrix adhesion. These heterogeneous phenotypes reflect...
ORGANISM(S): Homo sapiens 
2010-03-23 | E-GEOD-20285 | biostudies-arrayexpress
UnknownImpact of Vitamin E supplementation on vascular function in haptoglobin genotype stratified diabetes patients (EVAS Trial): a randomised controlled trial.
Not available
S-EPMC7186220 | biostudies-literature
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-70279 | biostudies-arrayexpress
UnknownDevelopment of a Multifunctional Edible Coating and Its Preservation Effect on Sturgeon (Acipenser baeri♀× Acipenser schrenckii♂) Fillets during Refrigerated Storage at 4 °C.
Not available
S-EPMC9655360 | biostudies-literature
TranscriptomicsExpression data of Hepatocellular Carcinoma
Expression profiling of Xenografts of Hepatocellular Carcinoma Keywords: Human Cancer Briefly, primary HCCs obtained during liver resection were minced into fine fragments capable of passing through an 18-gauge needle, mixed in a 1:1 (v/v) ratio with Matrigel (Collaborative Research, Bedford, MA) an...
ORGANISM(S): Homo sapiens 
2008-11-01 | E-GEOD-6465 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of H3K56ac in Drosophila melanogaster Kc167 cell lines with NICD overexpression
The conserved Notch pathway functions in diverse developmental and disease-related processes, requiring mechanisms to ensure appropriate target-selection and gene activation in each context. To investigate, we partitioned Drosophila chromatin into different states, based on histone modifications, es...
ORGANISM(S): Drosophila melanogaster 
2015-07-01 | E-GEOD-66221 | biostudies-arrayexpress
Proteomics,MultiomicsAPOBEC3A is an Oral Cancer Prognostic Biomarker in Taiwanese Carriers of an APOBEC Deletion Polymorphism
Chen T-W, Lee C-C, Liu H, Wu C-S, Pickering CR, Huang P-J, et al., Nature Communications 8, Article number: 465 (2017) doi:10.1038/s41467-017-00493-9

Oral squamous cell carcinoma is a prominent cancer worldwide, p...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084250 | MassIVE
UnknownA diet containing cod backbone proteins attenuated the development of mesangial sclerosis and tubular dysfunction in male obese BTBR ob/ob mice.
Not available
S-EPMC10611847 | biostudies-literature
TranscriptomicsTranscription profiling by array of Arabidopsis plants after innoculation with isogenic Pseudomonas syringaie strains expressing one of four different avr genes
Gene expression profiles of a single Arabidopsis genotype (Col-0) in response to isogenic Pseudomonas syringae strains expressing one of four different cloned avr genes was studied (avrRpt2, avrRpm1, avrPphB, avrRps4; responses mediated by the R genes RPS2, RPM1, RPS5 and RPS4 ).
ORGANISM(S): Arabidopsis thaliana 
2008-02-29 | E-MEXP-1480 | biostudies-arrayexpress
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