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UnknownGlobal view of enhancer-promoter interactome in human cells.
Not available
S-EPMC4040567 | biostudies-literature
GenomicsTime-course HoxB4 ChIP-Seq during HSC development from ES cells
Efficient in vitro generation of hematopoietic stem cells (HSCs) from embryonic stem cells (ESCs) holds great promise for cell-based therapies of hematological diseases. To date, HoxB4 remains to be the most effective transcription factor (TF) whose over-expression in ESCs confers long-term repopula...
ORGANISM(S): Mus musculus 
2012-03-23 | E-GEOD-34013 | biostudies-arrayexpress
TranscriptomicsGene expression profiling and ChIP-Seq study of HoxB4-mediated HSC development from ES cells
This SuperSeries is composed of the following subset Series: GSE33953: Time-course transcriptome measure of HoxB4-mediated HSC development from ES cells GSE34013: Time-course HoxB4 ChIP-Seq during HSC development from ES cells Refer to individual Series
ORGANISM(S): Mus musculus 
2012-03-23 | E-GEOD-34014 | biostudies-arrayexpress
TranscriptomicsTime-course transcriptome measure of HoxB4-mediated HSC development from ES cells
Efficient in vitro generation of hematopoietic stem cells (HSCs) from embryonic stem cells (ESCs) holds great promise for cell-based therapies of hematological diseases. To date, HoxB4 remains to be the most effective transcription factor (TF) whose over-expression in ESCs confers long-term repopula...
ORGANISM(S): Mus musculus 
2012-03-23 | E-GEOD-33953 | biostudies-arrayexpress
UnknownGender Differences in Health Protective Behaviors During the COVID-19 Pandemic in Taiwan: An Empirical Study.
Not available
S-EPMC8077589 | biostudies-literature
TranscriptomicsA systems approach to delineate functions of YAP family members
Duplication of genes encoding transcription factors plays an essential role in driving phenotypic variation. Because regulation can occur at multiple levels, it is often difficult to discern how each duplicated factor achieves its regulatory specificity. In these cases, a systems approach may distin...
ORGANISM(S): Saccharomyces cerevisiae 
2008-02-03 | E-GEOD-10146 | biostudies-arrayexpress
TranscriptomicsRunx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells
The transcription factor RUNX1 is frequently mutated in myelodysplastic syndrome and leukemia. RUNX1 mutations can be early events, creating pre-leukemic stem cells that expand in the bone marrow. Here we show that, counter-intuitively, Runx1 deficient hematopoietic stem and progenitor cells (HSPCs)...
ORGANISM(S): Mus musculus 
2015-07-27 | E-GEOD-67609 | biostudies-arrayexpress
ProteomicsMulti-Omic analyses reveal aberrant differentiation trajectory with WNT1 Loss-of-Function in type XV osteogenesis imperfecta
Osteogenesis imperfecta (OI) is a serious genetic bone disorder characterized by congenital low bone mass, deformity and frequent fractures. Type XV OI is a moderate to severe form of skeletal dysplasia caused by WNT1 mutations. In this cohort study from southern China, we summarized the clinical ph...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD050841 | Pride
Human Bone Osteogenesis imperfecta 
TranscriptomicsDe Novo Transcriptomic Analysis of a High Lipid-producing Mutant in the Green Alga Dunaliella tertiolecta through RNA-Seq
Background: For many years, increasing demands for fossil fuels have met with limited supply. As a potential substitute and renewable source of biofuel feedstock, microalgae have received significant attention. However, few of the current algal species produce high lipid yields to be commercially vi...
ORGANISM(S): Dunaliella tertiolecta 
2015-07-23 | E-GEOD-70876 | biostudies-arrayexpress
ProteomicsSILAC experiments profiling of the proteome of WT and YiaC KO E.coli
SILAC experiments profiling of the proteome of WT and YiaC KO E.coli
ORGANISM(S): Escherichia Coli 
2021-12-11 | PXD030346 |
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