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TranscriptomicsAlteration of gene expression in MCF-7 cells induced by king cobra venom L-amino acid oxidase (OH-LAAO)
Alteration of gene expression in MCF-7 cells using array-based whole genome gene expression technology . Results provide useful information on the molecular events leading to cell death induced by L-amino acid oxidase enzyme. MCF-7 cells were treated with IC20 value of OH-LAAO or PBS (control). Trea...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-59382 | biostudies-arrayexpress
TranscriptomicsPhysiologic Hypoxia Promotes Maintenance of CML Stem Cells Despite Effective BCRM-bM-^HM-^RABL1 Inhibition
ABL1 kinase inhibitors such as imatinib mesylate (IM) are effective in managing chronic myelogenous leukemia (CML) but incapable of eliminating leukemia stem cells (LSCs), suggesting that kinaseM-bM-^HM-^Rindependent pathways support LSC survival. Given that the bone marrow hypoxic microenvironment ...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-48294 | biostudies-arrayexpress
TranscriptomicsExpression data from postnatal mouse brain regions of Ts1Cje and disomic C57BL/6 mice.
The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16 (MMU16), which is partially homologous to human chromosome 21. The mouse model develops various neuropathological features identified in DS individuals. We analysed the effect of partial triplication of the ...
ORGANISM(S): Mus musculus 
2014-07-23 | E-GEOD-49050 | biostudies-arrayexpress
UnknownGene expression-based model using formalin-fixed paraffin-embedded biopsies predicts overall survival in advanced-stage classical Hodgkin lymphoma.
Not available
S-EPMC3574267 | biostudies-literature
ProteomicsTarget deconvolution of SW016789 in human and mouse Beta cells
The target of SW016789 is unknown (PMCID: PMC9225822). This compound was identified in a high-throughput screen for insulin secretion modulators and was subsequently discovered to cause hypersecretory stress in beta cells. A photoaffinity probe was designed, Z629, based upon the structure of SW01678...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2024-03-13 | MSV000094310 | MassIVE
TranscriptomicsProfiling of spatio-temporally regulated transcripts during cerebral corticogenesis in the mouse
The cerebral cortex plays an important role in cognitive function and specialized perception in mammals and its development requires highly specific spatio-temporal control of gene expression. The study identified stage- and region-specific markers throughout cerebral corticogenesis at various impor...
ORGANISM(S): Mus musculus 
2009-09-25 | E-GEOD-15031 | biostudies-arrayexpress
TranscriptomicsExpression profiles of 186-gene signature in U.S. hepatitis C virus (HCV)-related liver cirrhosis
OBJECTIVE: The number of patients with HCV-related cirrhosis is increasing, leading to a rising risk of complications and death. Prognostic stratification in patients with early-stage cirrhosis is still challenging. We aimed to develop and validate a clinically useful prognostic index based on genom...
ORGANISM(S): Homo sapiens 
2014-08-22 | E-GEOD-54100 | biostudies-arrayexpress
UnknownResidual lung abnormality following COVID-19 hospitalisation is characterised by biomarkers of epithelial injury.
Not available
S-EPMC12860639 | biostudies-literature
UnknownImprovement in quality of life and psychological symptoms after treatment for primary aldosteronism: Asian Cohort Study.
Not available
S-EPMC8346187 | biostudies-literature
UnknownVariation in immunoglobulin use and impact on survival in myeloma.
Not available
S-EPMC11327709 | biostudies-literature
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