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ProteomicsOTUD3-Mediated Stabilization of SLC7A11 Drives Sunitinib Resistance by Suppressing Ferroptosis in Clear Cell Renal Cell Carcinoma
After cell lysis, the global proteomes of wild-type 786O and OTUD3-knockdown (KD) 786O cell lines were analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Label-free quantification (LFQ) was employed for comparative protein quantification, and tandem mass spectrometry data were...
ORGANISM(S): Homo sapiens (Human) 
2025-08-15 | PXD064004 | Pride
786o shotud3 lc/msms 
ProteomicsA chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
Through chemical probe screening, we uncovered a novel mechanism of RNA splicing in paclitaxel-resistant TNBC and identified PRMTs as therapeutic targets.
ORGANISM(S): Homo Sapiens 
PXD053336 |
ProteomicsProteomics comparison of protein changes in H1299 cell before and after resistance to cdk4/6 inhibitors
This is the raw proteomics data of H1299 cell before and after resistance to cdk4/6 inhibitors
ORGANISM(S): Homo Sapiens 
2023-05-15 | PXD042216 |
TranscriptomicsA comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequence Quality Control consortium
We present primary results from the Sequencing Quality Control (SEQC) project, coordinated by the United States Food and Drug Administration. Examining Illumina HiSeq, Life Technologies SOLiD and Roche 454 platforms at multiple laboratory sites using reference RNA samples with built-in controls, we ...
ORGANISM(S): Homo sapiens 
2014-08-08 | E-GEOD-56457 | biostudies-arrayexpress
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