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TranscriptomicsDevelopment of gene expression signatures for miR-340 overexpressing human glioma-initiating cells (GICs)
To identify functional targets of miR-340, we compared the gene expression profiles of miR-340 overexpressing human GICs with the profiles of their parental cells. The precursor form of miR-340 or control miRNA was overexpressed in glioma cells using miRNA lentiviral particles. The cells were incuba...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-61078 | biostudies-arrayexpress
TranscriptomicsDevelopment of microRNA (miRNA) expression signatures for human glioma-initiating cells (GICs)
To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the human GICs and glioma cell lines and neural stem cells by miRNA microarrays. We examined the miRNA expression profiles of five human GICs that were obtained from human glioma sampl...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-61079 | biostudies-arrayexpress
TranscriptomicsDevelopment of microRNA (miRNA) expression signatures for mouse glioma-initiating cells (GICs)
To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the mouse GICs, NSCL61 and OPCL61, showing characteristic features of cancer stem cell, and their parental cells by miRNA microarrays. neural stem cells, glioma-initiating cells (GICs)...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-61080 | biostudies-arrayexpress
TranscriptomicsMepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
For the clinical treatment of chronic obstructive pulmonary disease (COPD), it is important not only to improve the airflow limitation by bronchodilation but also to suppress emphysema by controlling inflammation. In this study, we have screened for compounds that prevent elastase-induced airspace ...
ORGANISM(S): Mus musculus 
2013-11-13 | E-GEOD-50836 | biostudies-arrayexpress
TranscriptomicsDNA microarray analysis of PBMCs from Behçet’s disease (BD) patients
To examine if gene expression profiles of many Behçet’s disease (BD) patients are commonly abnormal compared to those of healthy volunteers, we performed a genome-wide complementary DNA microarray analysis using an Agilent Hu44K array; RNA samples were isolated from the PBMCs of 41 individual BD ...
ORGANISM(S): Homo sapiens 
2016-01-21 | E-GEOD-70403 | biostudies-arrayexpress
TranscriptomicsLow SLC22A7 expression in noncancerous liver promotes hepatocellular carcinoma occurrence - a prospective study
Background & Aims: The recurrence determines the postoperative prognosis of patients with hepatocellular carcinoma (HCC). It is unknown whether de novo HCCs derive from the liver with disability of an organic anion transport. This study was designed to elucidate the link between such transporters an...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-40873 | biostudies-arrayexpress
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