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MetabolomicsComputational mass spectrometry accelerates C=C position-resolved untargeted lipidomics using oxygen attachment dissociation
Mass spectrometry-based untargeted lipidomics has revealed the lipidome atlas of living organisms at the molecular species level. Despite the double bond (C=C) position being a crucial factor for enzyme preference, cellular membrane milieu, and biological activity, the C=C defined structures have no...
2022-11-09 | MTBLS5861 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
TranscriptomicsTranscriptome analysis of gibberellin-signaling mutants in rice
This Series is composed of the following Samples: GSM375647: Taichung 65_shoot_replicate 1 GSM375648: Taichung 65_shoot_replicate 2 GSM375649: Taichung 65_shoot_replicate 3 GSM375765: gid1-3_ shoot_replicate 1 GSM375766: gid1-3_ shoot_replicate 2 GSM375767: gid1-3_ shoot_replicate 3 GSM375769: gid2-...
ORGANISM(S): Oryza sativa 
2009-04-21 | E-GEOD-15046 | biostudies-arrayexpress
TranscriptomicsProstates of rats with induced partial bladder outlet obstruction and the effect of Eviprostat on those changes
Prostatic inflammation plays a role in the progression of benign prostatic hyperplasia (BPH). Eviprostat is an antiinflammatory and antioxidant phytotherapeutic agent widely used to treat lower urinary tract symptoms in BPH. However, because Eviprostat is a mixture of compounds from multiple natural...
ORGANISM(S): Rattus norvegicus 
2010-04-09 | E-GEOD-16063 | biostudies-arrayexpress
ProteomicsAnalysis of Mettl1 interacting proteins in Drosophila
Mass spec analysis was performed to identify interacting proteins with FLAG-tagged Mettl1 in Drosophila ovary.
ORGANISM(S): Drosophila Melanogaster (fruit Fly) 
2024-08-20 | PXD044501 | JPOST Repository
TranscriptomicsMethylation profiling classifies HIV-associated lymphoma
HIV-positive patients have a higher risk of non-Hodgkin's lymphoma with poor prognostic features. To characterize features of HIV-associated lymphoma, we compared the genome-wide DNA methylation profiles in between 11 HIV-associated and 20 non-HIV lymphoma samples by Illumina Infinium HumanMethylati...
ORGANISM(S): Homo sapiens 
2014-01-30 | E-GEOD-42372 | biostudies-arrayexpress
UnknownEvolution and diversification of the plant gibberellin receptor GID1.
Not available
S-EPMC6099883 | biostudies-literature
TranscriptomicsMethylation profiling categorizes HIV-associated lymphomas in two distinctive groups
HIV-positive patients have a higher risk of non-Hodgkin's lymphoma with poor prognostic features. To characterize features of HIV-associated lymphoma, we compared the DNA methylation profiles of 803 cancer-related genes in between 9 HIV-associated and 12 non-HIV lymphoma samples by Illumina GoldenGa...
ORGANISM(S): Homo sapiens 
2014-01-30 | E-GEOD-42626 | biostudies-arrayexpress
UnknownGWAS with principal component analysis identifies a gene comprehensively controlling rice architecture.
Not available
S-EPMC6800328 | biostudies-literature
TranscriptomicsGlobal expression analysis of HNF4alpha and HNFgamma-mediated transcriptional control
Hepatocyte nuclear factor-4α (HNF4α, NR2A1) is a nuclear receptor which has a critical role in hepatocyte differentiation and the maintenance of homeostasis in the adult liver. However, a detailed understanding of native HNF4α in the steady state remains to be elucidated. Here we report the native H...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-18973 | biostudies-arrayexpress
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