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TranscriptomicsWT vs gntR1 mutant gene expression profiles
The transcriptional regulator GntR1 downregulates the genes for gluconate catabolism and pentose phosphate pathway in Corynebacterium glutamicum. Gluconate lowers the DNA binding affinity of GntR1, which is probably the mechanism of gluconate-dependent induction of these genes. In addition, GntR1 po...
ORGANISM(S): Corynebacterium glutamicum 
2014-07-15 | E-GEOD-58631 | biostudies-arrayexpress
TranscriptomicsChip-chip analysis of C. glutamicum GntR1
The transcriptional regulator GntR1 downregultates the genes for gluconate catabolism and pentose phosphate pathway in Corynebacterium glutamicum. Gluconate lowers the DNA binding affinity of GntR1, which is probably the mechanism of gluconate-dependent induction of these genes. In addition, GntR1 p...
ORGANISM(S): Corynebacterium glutamicum 
2014-07-15 | E-GEOD-58632 | biostudies-arrayexpress
TranscriptomicsThe induced APL cells generated by the transplantation of PML-RARA-transduced human CD34+ hematopoietic cells into immunodeficient mice
A humanized in vivo APL model has been established utilizing the retroviral transduction of PML-RARA into human CD34+ hematopoietic cells and the transplantation of these cells into immunodeficient mice. The resultant leukemia recapitulated human APL phenotypically, and was clustered in the same cat...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-49344 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of the C. glutamicum deletion mutant of rnc, which encodes an RNase III homolog
The Corynebacterium glutamicum R cgR_1959 gene encodes an endoribonuclease of the RNase III family. Deletion mutant of cgR_1959 (Δrnc mutant) showed an elongated cell shape, and presence of several lines on the cell surface, indicating a required of RNase III for maintaining normal cell morphology ...
ORGANISM(S): Corynebacterium glutamicum 
2016-01-17 | E-GEOD-75080 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of serous ovarian cancer samples
To elucidate the mechanisms of rapid progression of serous ovarian cancer, gene expression profiles from forty-three ovarian cancer tissues comprising eight early stage and thirty-five advanced stage tissues were performed using oligonucleotide microarrays of 18,716 genes. By non-negative matrix fac...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-12470 | biostudies-arrayexpress
UnknownCoordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells.
Not available
S-SCDT-EMBOJ-2019-103949 | biostudies-other
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