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ProteomicsDIA-MS based proteome analysis of HL-60 cells treated with new anti-cancer drug (TAS4464)
We investigated the protein change of HL-60 cells with TAS4464 treatment in time series (0 h, 1h, 4h, 8h, 16h, 24h) by overlapping DIA-MS based proteome analysis. Spectral library was created by analyzing pooled samples by five gas-phase fractionated overlapping DIA-MS measurements.
ORGANISM(S): Homo Sapiens (human) 
2021-08-20 | PXD021012 | JPOST Repository
TranscriptomicsMepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
For the clinical treatment of chronic obstructive pulmonary disease (COPD), it is important not only to improve the airflow limitation by bronchodilation but also to suppress emphysema by controlling inflammation. In this study, we have screened for compounds that prevent elastase-induced airspace ...
ORGANISM(S): Mus musculus 
2013-11-13 | E-GEOD-50836 | biostudies-arrayexpress
UnknownComparative analysis of aldosterone and renin assays for primary aldosteronism screening.
Not available
S-EPMC11522277 | biostudies-literature
UnknownIdentification of genotype-biochemical phenotype correlations associated with fructose 1,6-bisphosphatase deficiency.
Not available
S-EPMC10382519 | biostudies-literature
UnknownLiver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis.
Not available
S-EPMC9478157 | biostudies-literature
UnknownTAS4464, a NEDD8-activating enzyme inhibitor, activates both intrinsic and extrinsic apoptotic pathways via c-Myc-mediated regulation in acute myeloid leukemia.
Not available
S-EPMC7892340 | biostudies-literature
UnknownMicroRNA-874 targets phosphomevalonate kinase and inhibits cancer cell growth via the mevalonate pathway.
Not available
S-EPMC9630378 | biostudies-literature
Unknownp53-inducible lncRNA LOC644656 causes genotoxic stress-induced stem cell maldifferentiation and cancer chemoresistance.
Not available
S-EPMC12102190 | biostudies-literature
GenomicsIntegrated genetic and epigenetic analysis defines novel molecular clusters in rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood. To unravel the genetic/epigenetic basis of RMS, we studied 60 RMS cases using whole exome/transcriptome sequencing, copy number (CN) profiling, and DNA methylome analysis. Based on DNA methylation patterns, RMS was clustered...
EGAS00001000884 | EGA
GenomicsRMS_Infinium450K
Infinium 450K in Rhabdomyosarcoma
EGAD00010000897 | EGA
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