Tang Benjamin M BM

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Critically ill patients with either gram-positive sepsis or gram-negative sepsis

Objective: It is unclear whether the host response of gram-positive sepsis differs from gram-negative sepsis at a transcriptome level. Using microarray technology, we compared the gene-expression profiles of gram-positive sepsis and gram-negative sepsis in critically ill patients. Design: A pros...

ORGANISM(S): Homo sapiens

2010-05-25 | E-GEOD-6535 | biostudies-arrayexpress

Whole blood transcriptome of survivors and nonsurvivors of sepsis

There is currently no reliable tool available to measure immune dysfunction in septic patients in the clinical setting. This proof-of-concept study assesses the potential of gene expression profiling of whole blood as a tool to monitor immune dysfunction in critically ill septic patients. Whole bloo...

ORGANISM(S): Homo sapiens

2014-02-04 | E-GEOD-54514 | biostudies-arrayexpress

Radical prostatectomy specimens with and without TMPRSS2:ERG fusion from 139 patients with prostate in a Toronto cohort

Prostate tumors with the gene fusion TMPRSS2:ERG have been reported to have a significantly higher risk of recurrence compared with tumors lacking the fusion. Tumors from 139 patients who underwent radical prostatectomy were analyzed for the expression of 502 cancer-related genes to identify genes d...

ORGANISM(S): Homo sapiens

2009-10-22 | E-GEOD-18655 | biostudies-arrayexpress

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

Not available

S-EPMC3037413 | biostudies-literature

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.

Not available

S-EPMC3723315 | biostudies-literature

Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals.

Not available

S-EPMC12418676 | biostudies-literature

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.