Tang Jiayu J - OmicsDI

We developed an in situ cross-linking coupled reversed-phase liquid chromatography-based co-fractionation mass spectrometry (XL-CoFrac-MS) platform to analyze drug-induced protein complex changes. A software tool, ChromaQuant, was built to automate chromatographic peak quantification. Using RS4;11 l...

ORGANISM(S): Homo Sapiens

PXD067673 |

Comparison of seed proteome of weak dormant rice variety Zhonghua11 and strong dormant rice LL at the beginning of harvest

Rice seed dormancy is an important agronomic trait, but its regulation mechanism is not very clear. In this experiment, the proteome of weak dormant Zhonghua11 and strong dormant LL was determined at the beginning of harvest, and the differentially expressed proteins were analyzed to try to find out...

ORGANISM(S): Oryza Sativa

2023-02-23 | PXD040365 |

Nascent proteome reveals key regulators in the development of alcoholic liver disease

Alcoholic liver disease (ALD) poses a significant global health challenge, and the global proteome will change dynamically and dramatically for the response to alcohol stress. However, due to the lack of method for labeling and identification of tissue-specific nascent proteome in living mouse, the ...

ORGANISM(S): Homo Sapiens Mus Musculus

PXD051725 |

LiP-small molecule mapping of Farrerol

Limited proteolysis combined with mass spectrometry of farrerol treated. Briefly, cell lysates containing approximately 500 μg of total protein sample were incubated with farrerol or vehicle (DMSO) for 10 min at 25 °C. Proteinase K (5 μg, Sigma–Aldrich) was added simultaneously to each sample for t...

ORGANISM(S): Homo Sapiens

PXD036308 |