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Our study identify that methionine inhibits N-terminus of GSDME (GSDME-NT) -mediated pyroptosis by dampening its endocytotic degradation. Thus,the binding proteins of GSDME-NT are detected in the presence or absence of Methionine for futher exploration。
ORGANISM(S): Homo Sapiens 
2025-01-19 | PXD059954 |
Our study identify that methionine inhibits N-terminus of GSDME (GSDME-NT) -mediated pyroptosis by dampening its endocytotic degradation. This process is regulated by methionine metabolite spermidine,which can bind with proteins to regulate their biological function. Thus,the binding proteins of sp...
ORGANISM(S): Homo Sapiens 
2025-01-21 | PXD060003 |
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