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MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7711 | MetaboLights
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7713 | MetaboLights
TranscriptomicsTracing pluripotency of human early embryos and embryonic stem cells by single cell RNA-seq
Find the casual relationship between gene expression network and cellular phenotype at single cell resolution. We collected donated human pre-implatation embryos, and the embryonic stem cells derived from them, isolate individual cells, prepared single cell cDNAs, and sequenced them by HiSeq2000. Th...
ORGANISM(S): Homo sapiens 
2013-08-10 | E-GEOD-36552 | biostudies-arrayexpress
UnknownInteraction between Porcine Alveolar Macrophage-Tang Cells and Streptococcus suis Strains of Different Virulence: Phagocytosis and Apoptosis.
Not available
S-EPMC9863715 | biostudies-literature
GenomicsCharacterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization
Recent epigenomic studies have predicted thousands of potential enhancers in the human genome. However, there has not been systematic characterization of target promoters for these potential enhancers. Using H3K4me2 as a mark for active enhancers, we identified genome-wide enhancer-promoter interact...
ORGANISM(S): Homo sapiens 
2012-01-24 | E-GEOD-32677 | biostudies-arrayexpress
UnknownScreening of Antiviral Components of Ma Huang Tang and Investigation on the Ephedra Alkaloids Efficacy on Influenza Virus Type A.
Not available
S-EPMC6747051 | biostudies-literature
UnknownSingle-molecule long-read sequencing of the full-length transcriptome of Rhododendron lapponicum L.
Not available
S-EPMC7174332 | biostudies-literature
UnknownEnhancing the thermostability of α-L-rhamnosidase from Aspergillus terreus and the enzymatic conversion of rutin to isoquercitrin by adding sorbitol.
Not available
S-EPMC5327507 | biostudies-literature
TranscriptomicsUncovering small RNA-mediated responses to cold stress in a wheat thermosensitive genic male sterile line by deep sequencing
The male sterility of thermosensitive genic male sterile (TGMS) lines of wheat (Triticum aestivum) is strictly controlled by temperature. The early phase of anther development is especially susceptible to cold stress. MicroRNAs (miRNA) play an important role in plant development and in responses to ...
ORGANISM(S): Triticum aestivum 
2012-03-29 | E-GEOD-36867 | biostudies-arrayexpress
UnknownDissecting the Underlying Pharmaceutical Mechanism of Chinese Traditional Medicine Yun-Pi-Yi-Shen-Tong-Du-Tang Acting on Ankylosing Spondylitis through Systems Biology Approaches.
Not available
S-EPMC5647417 | biostudies-literature
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