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Our results introduce interleukin (IL)-11 as a new cytokine that may play a role in the development of the autoimmune response in patients with relapsing remitting multiple sclerosis (RR MS). IL-11 was found to be the highest up-regulated cytokine in the serum and cerebrospinal fluid (CSF) from pat...
ORGANISM(S): Homo sapiens 
In our study, we apply isobaric tag for relative and absolute quantitation (iTRAQ) followed by multidimensional liquid chromatography and tandem MS analysis(LC-MS-MS). The iTRAQ labeling were performed according to the manufacturer's protocol (Applied Biosystems).8 groups of samples were labeled and...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-24 | PXD006437 | Pride
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
Angiogenesis plays a key role in tumor metastasis. Many genes may act in this process including formation of vessels, immune evasion,etc. Different gene expression profiles between lymphoma endothelium cells and reactive lymph node-derived endothelium cells may uncover these genes. And intensive mec...
ORGANISM(S): Homo sapiens 
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