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MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae pGAL1-MKS1, pGAL1-NNK1, and pGAL1-FMP48 overexpression
Analysis of the transcriptional effects of pGAL1-MKS1, pGAL1-NNK1, and pGAL1-FMP48 overexpression. BY4700 gal1::NAT ura3delta0 S. cerevisiae cells carrying a [pGAL1-MKS1-HA, URA3, CEN], [pGAL1-NNK1-HA, URA3, CEN], or [pGAL1-FMP48-HA, URA3, CEN] plasmid, or empty vector BG1805, were grown to early lo...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-25 | E-MEXP-2171 | biostudies-arrayexpress
ProteomicsPosternak_PROTACdegradation_P124_Lumos
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E. This dataset provides a proteome-wide view of protein degradation after treatment...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-10 | MSV000085271 | MassIVE
ProteomicsPosternak_PROTACagainstBRAFV600E_P124_Lumos
The files are associated with a manuscript submitted for publication by Ganna Posternak et al. The main goal of this paper was functionally characterize the mechanism of action of a PROTAC designed to target BRAFV600E.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-11-07 | MSV000084551 | MassIVE
ProteomicsProteomic profiling and tumor microenvironment characterization reveal molecular and immunological hallmarks of left-sided and right-sided colon cancer tumorigenesis
The protein landscapes of LSCC and RSCC were constructed, and the hallmarks of tumorigenesis and characteristics of TME for LSCC and RSCC were identified. These findings improved our understanding of LSCC and RSCC and may facilitate the development of diagnostic or therapeutic targets for LSCC and R...
ORGANISM(S): Homo Sapiens 
2023-06-13 | PXD042962 |
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