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To identify the downstream mRNA targeted by CDIPTOSP/STAU1 for degradation, RNA-Seq analyses were performed on SKOV3 cells transfected with si-NC (control), si-CDIPTOSP, and si-STAU1.
ORGANISM(S): Homo sapiens 
YAMC (young adult mouse colon) cells are a conditionally immortalized mouse colonic intestinal epithelial cell line derived from the Immortimouse.Prior to each experiment, cells were plated at a density of 7.5 x 105 cells per p100mm dish.Cells were treated with LGG (the probiotic Lactobacillus GG ) ...
ORGANISM(S): Mus musculus 
Brr2 is a DExD/H-box helicase responsible for U4/U6 unwinding, a critical step in spliceosomal activation. Brr2 contains an N-terminal domain and two tandem sets of a helicase-like domain followed by a Sec63 domain with unknown function. We determined the crystal structure of the second Sec63 doma...
ORGANISM(S): Saccharomyces cerevisiae 
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