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Metabolomicswidely targeted metabolomic analysis

Based on widely targeted metabolomic analysis, we explored the differences in metabolite composition and content of tomato fruits with different genotypes or exogenous metabolites were added. In addition, we also investigated the effects of different treatments on the composition and content of b...

2025-12-14 | MTBLS13506 | MetaboLights
MetabolomicsDried blood spots analysis for targeted and non-targeted exposomics

Dried blood spots (DBS) are an established sample type, widely used in newborn screening programs for monitoring metabolic diseases. Their minimally invasive nature offers great promise for assessing chemical exposures, particularly during early life stages and in large-scale epidemiological stud...

2025-10-09 | MTBLS13065 | MetaboLights
MetabolomicsExposomic Biomonitoring of Polyphenols by Non-Targeted Analysis and Suspect Screening

Polyphenols, prevalent in plants and fungi, are investigated intensively in nutritional and clinical settings because of their beneficial bioactive properties. Due to their complexity, analysis with untargeted approaches is favorable, which typically use high-resolution mass spectrometry (HRMS) r...

2025-08-07 | MTBLS7564 | MetaboLights
MetabolomicsCompilation of transcriptomics, non-targeted metabolomics and targeted metabolomics data in bovine mammary epithelial cells stimulated by ten different essential amino acids (Targeted metabolomics)

Divergence in the targeted amino acid profilings of bovine mammary epithelial cells (BMECs) were systematically captured with regard to 10 individual essential amino acid (EAA) availability. BMECs cultured in 6-well plates were first serum-starved overnight and subsequently assigned to 1 of 12 tr...

2024-03-04 | MTBLS3956 | MetaboLights
MetabolomicsTargeted metabolomics analysis of scallop and ascidian tissues
Ascidian is an invasive fouling species within marine ecosystem. The fouling ascidians usually attach on bivalve aquaculture facilities, which is likely related to the influence of certain chemical factors. To investigate the key chemical factors involved in inducing attachment and metamorphosis of ...
2026-01-12 | MTBLS11935 | MetaboLights
MetabolomicsNon-targeted metabolomics analysis of synovial fluid from TMD patients
This study performed non-targeted metabolomics detection on 62 human joint cavity lavage fluid samples using UHPLC-QE-MS. Metabolites were extracted with methanol:acetonitrile (1:1), separated on a Waters ACQUITY UPLC BEH Amide column, and detected by Orbitrap Exploris 120 mass spectrometer in both ...
2026-09-23 | MTBLS14238 | MetaboLights
MetabolomicsTargeted metabolomics analysis by LC-MS/MS for BMDCs infected with VSV
Virus-infected cells often exhibit dramatic cellular changes accompanied by altered mitochondrial function. The contribution of factors shaping the inner mitochondrial membrane (IMM) and cristae architecture on viral replication is insufficiently understood. Single cell transcriptomics applying vesi...
2025-06-18 | MTBLS12438 | MetaboLights
MetabolomicsStructure-based non-targeted mass spectrometry imaging analysis of dried long pepper
Not available
ORGANISM(S): Piper longum 
ST002144 | MetabolomicsWorkbench
MetabolomicsLC-MS/MS targeted analysis of ferroptosis-associated phospholipid peroxidation in KIF11-depleted HRECs

Human retinal vascular endothelial cells (HRECs) were transfected with lentivirus encoding either KIF11-targeting shRNA or a non-targeting control. KIF11-depleted and control cells were then subjected to lipid extraction followed by LC–MS/MS–based targeted analysis of ferroptosis-associated phosp...

2026-02-13 | MTBLS12912 | MetaboLights
MetabolomicsDiverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood
During human fasting, metabolic markers, including butyrates, carnitines, and branched-chain amino acids, are upregulated for energy substitution through gluconeogenesis and use of stored lipids. We performed non-targeted, accurate semiquantitative metabolomic analysis of human whole blood, plasma, ...
2019-09-11 | MTBLS549 | MetaboLights
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