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TranscriptomicsExpression analysis in yeast model of Huntington's disease (HD)
Expressing a mutant fragment of huntingtin (Htt) in yeast produces several HD-relevant phenotypes. We used microarrays to study global change in expression induced by this mutant htt fragment. Expression was also analysed in three suppressor deletion strains expressing a toxic mutant htt fragment: ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-11-09 | E-GEOD-18644 | biostudies-arrayexpress
TranscriptomicsExpression analysis of circadian light response in Drosophila recombinant inbred lines (RIL)
The aim of this study was to identify quantitative trait loci (QTL) associated with variation in circadian photosensitivity in Drosophila, by measuring the locomotor response to early night light pulse (Zt15). We used QTL mapping of recombinant inbred lines (RIL), which was followed by microarrays e...
ORGANISM(S): Drosophila melanogaster 
2016-02-09 | E-GEOD-77116 | biostudies-arrayexpress
TranscriptomicsExpression analysis of circadian light response in Drosophila
Light is a strong environmental cue that resets the circadian clock rhythm. We have used Affymetrix microarrays to profile the Drosophila head transcriptome response following a brief light pulse during the early night. Comparison of control (un-pulsed) and experimental flies reveal large number of...
ORGANISM(S): Drosophila melanogaster 
2014-07-23 | E-GEOD-39578 | biostudies-arrayexpress
TranscriptomicsWhole-body transcriptomics of Nasonia vitripennis females as they respond to sex allocation cues
Linking the evolution of the phenotype to the underlying genotype is a key aim of evolutionary genetics and is crucial to our understanding of how natural selection shapes a trait. Here we consider the genetic basis of sex allocation behaviour in the parasitoid wasp Nasonia vitripennis using a trans...
ORGANISM(S): Nasonia vitripennis 
2015-11-11 | E-GEOD-74241 | biostudies-arrayexpress
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