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MetabolomicsTaurine ameliorates oxidative stress of BMSCs and promotes osteogenesis in irradiated jaws
Osteoradionecrosis of the jaw (ORNJ) is a complication after head and neck radiotherapy that severely affects patients’ quality of life. Currently, an overall understanding of microenvironmental factors of ORNJ is still lacking. Here, we reveal the activation of taurine metabolism in irradiated mand...
2024-07-08 | MTBLS10284 | MetaboLights
MetabolomicsMulti-omics reveals taurine-mediated rumen microbial remodeling mitigates high-starch-diet-induced systemic inflammation and oxidative stress in fattening cattle

Background: With the pursuit of rapid intramuscular fat deposition in beef cattle, basal diets have increasingly shifted toward grain-based, energy-dense formulations. However, high-starch dietary regimens may induce host metabolic dysregulation, which is closely linked to both ruminal microbial ...

2025-09-25 | MTBLS13041 | MetaboLights
MetabolomicsB-cell Translocation Gene 2 Inhibits UFMylation Modification of FMO1 thus Restricting Taurine Synthesis and Exacerbating Ferroptosis in Hepatic Ischemia-Reperfusion Injury

Hepatic ischemia-reperfusion (I/R) injury is a common complication occurs during liver transplantation. However, the mechanisms underlying hepatic I/R injury have not been fully elucidated. B-cell translocation gene 2 (Btg2) has been implicated in the development of various diseases. However, its...

2026-03-07 | MTBLS11677 | MetaboLights
TranscriptomicsMouse gestational protein restriction: Newborn offspring liver and hindleg muscle
Gestational protein restriction is a model for low birth size. We hypothesized that taurine supplementation would protect against changes in newborn liver and muscle caused by a maternal low protein diet. Pregnant mouse dams were subjected to different diet schemes from day 1 of pregnancy until birt...
ORGANISM(S): Mus musculus 
2009-11-07 | E-GEOD-12730 | biostudies-arrayexpress
TranscriptomicsGestational taurine supplementation of mice: effect on offspring gene expression in liver and skeletal muscle
Taurine is known to be important for fetal well being and to be able to prevent effects of a low birthweight phenotype when supplemented to pregnant dams. We hypothesized that gestational taurine supplementation would affect gene expression level in 4w offspring liver and skeletal muscle. Pregnant m...
ORGANISM(S): Mus musculus 
2010-12-01 | E-GEOD-20577 | biostudies-arrayexpress
ProteomicsTaurine is covalently incorporated into alpha tubulin
Taurine is covalently incorporated into alpha tubulin
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Gallus Gallus (ncbitaxon:9031) 
2020-04-27 | MSV000085344 | MassIVE
ProteomicsEcophysiology and interactions of a novel taurine-respiring bacterium in the mouse gut
Taurine-respiring gut bacteria produce H2S with ambivalent impact on host health. We report the isolation and ecophysiological characterization of the first taurine-respiring mouse gut bacterium. Taurinivorans muris represents a new widespread species that differs from the human gut sulfidogen Bilop...
ORGANISM(S): Desulfovibrionaceae bacterium LT0009 
2023-08-11 | PXD044449 | Pride
Mouse gut Taurinivorans muris Taurine-respiration 
TranscriptomicsMultiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse
Taurine was previously reported to increase the proliferation of neural precursor cells (NPCs) from subventricular zone of the mouse brain. The results of a study that aimed to understand the mechanisms of this effect are presented here. A gene expression profile analysis indicated that genes regula...
ORGANISM(S): Mus musculus 
2013-12-21 | E-GEOD-53547 | biostudies-arrayexpress
MetabolomicsPTER is an N-acetyltaurine hydrolase that regulates feeding and obesity

Taurine is a conditionally essential micronutrient and one of the most abundant amino acids in humans1-3. In endogenous taurine metabolism, dedicated enzymes are involved in biosynthesis of taurine from cysteine as well as the downstream metabolism of secondary taurine metabolites4,5. One such ta...

2024-09-11 | MTBLS10408 | MetaboLights
TranscriptomicsTaurine transporter (SLC6A6)-deficient skeletal muscle
Analysis of skeletal muscle from taurine transporter (TauT) knockout mice at 3 or 18 months of age. Knocking out TauT result in a decrease in muscle cell size, impaired exercise capacity and accelerated muscle aging. Results provide molecular insights into physiological role of taurine. Sample: 12
ORGANISM(S): Mus musculus 
2014-05-08 | E-GEOD-57373 | biostudies-arrayexpress
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