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Gene expression profile from the bicuspid aortic valve(BAV), tricuspid aortic valve(TAV) and control samples.
BACKGROUND: The vast majority of thoracic aortic aneurysms (TAAs) are observed either together with a bicuspid aortic valve (BAV), a common congenital disorder, or in idiopathic cases such as patients with a normal tricuspid aortic valve (TAV). The main objective of our study was to identify shared ...
ORGANISM(S): Homo sapiens 
Patients with bicuspid aortic valve (BAV) have increased risk of thoracic ascending aortic aneurysm (AscAA) and dissection compared to those with a normal tricuspid aortic valve (TAV). The present study was undertaken to evaluate whether differences in gene expression exist in aortas from BAV and TA...
ORGANISM(S): Homo sapiens 
bulk RNA sequencing was employed to investigate the discrepancies in transcript levels between TAV and BAV in valve tissues of end-stage CAVD.
ORGANISM(S): Homo sapiens 
2025-12-11 | GSE284003 | GEO
and with higher incidence if associated to bicuspid aortic valve (BAV) for unknown reasons. TAA is usually diagnosed fortuitously and the lack of effective drug therapy to delay progression and avoid dissection lies in the limited knowledge of pathophysiology. Objectives. We aimed to identify the mo...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD043062 | Pride
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