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MetabolomicsCross-modal Integration of Metabolomics and Cardiac Functionality Captures Dynamic Metabotoxic Effects of Doxorubicin in Engineered Heart Tissues

Functional stem cell-derived heart models offer new avenues for preclinical, animal-free physiological assessment of drug cardiotoxicity. Yet, comprehensive molecular profiling in these models remains limited, leaving key metabolic drivers of cardiotoxicity unexplored.

Here, we leveraged an...

2025-12-07 | MTBLS13225 | MetaboLights
UnknownSIFTS: Structure Integration with Function, Taxonomy and Sequences resource.
Not available
S-EPMC3531078 | biostudies-literature
UnknownSIFTS: updated Structure Integration with Function, Taxonomy and Sequences resource allows 40-fold increase in coverage of structure-based annotations for proteins.
Not available
S-EPMC6324003 | biostudies-literature
UnknownFungal secretome profile categorization of CAZymes by function and family corresponds to fungal phylogeny and taxonomy: Example Aspergillus and Penicillium.
Not available
S-EPMC7083838 | biostudies-literature
UnknownIdentifying Optimal Machine Learning Approaches for Microbiome-Metabolomics Integration with Stable Feature Selection.
Not available
S-EPMC12236860 | biostudies-literature
UnknownIntegration of multi-omics data to elucidate keystone unknown taxa within microbialite-forming ecosystems.
Not available
S-EPMC10416242 | biostudies-literature
ProteomicsMulti-Omics Integration Highlights the Role of Ubiquitination in Endometriosis Fibrosis
In this study, we comprehensively profiled the ubiquitination landscape of endometriosis for the first time. Through proteomics, transcriptomics, and ubiquitylomics analyses of endometrial tissues from two patient cohorts, we uncovered significant dysregulation of ubiquitin-related enzymes and ubiqu...
ORGANISM(S): Homo Sapiens 
PXD036497 |
UnknownPANDORA: keyword-based analysis of protein sets by integration of annotation sources.
Not available
S-EPMC206469 | biostudies-literature
UnknownHayai-Annotation Plants: an ultra-fast and comprehensive functional gene annotation system in plants.
Not available
S-EPMC6821316 | biostudies-literature
MetabolomicsMulti-omics analysis of thermogenic lipolysis in brown adipocytes

The integration of omics technologies into molecular biological research has transformed it into a field where a system can be investigated as a whole by combining information from multiple biochemical layers. This extension of traditional molecular biology, where various data sources are conside...

2025-11-12 | MTBLS12307 | MetaboLights
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