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TranscriptomicsDevelopment of gene expression signatures for latent and clinical tuberculosis (TB)
For further identify the differentiation between latent and clinical tuberculosis (TB), we employed whole genome microarray expression profiling to study genes with significant expression change in peripheral CD4+T cells between healthy control, latent tuberculosis (LTB) and clinical tuberculosis (T...
ORGANISM(S): Homo sapiens 
2012-08-06 | E-GEOD-27882 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of caseous human pulmonary TB granulomas derived from TB patients
Most individuals infected with Mycobacterium tuberculosis can control the infection by forming and maintaining TB granulomas at the local infection foci. However, when the chronic infection (also known as latency) becomes active, the caseous center of TB granuloma enlarges, and it liquefies and cav...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-20050 | biostudies-arrayexpress
GenomicsButyrivibrio sp. TB strain:TB
Butyrivibrio sp. TB strain:TB Genome sequencing
PRJNA254903 | ENA
TranscriptomicsBlood Transcriptional Profiles of TB in South Africa
The aim of this study was to compare the transcriptional response to TB in regions of different incidence / prevalence. Experimental Design: Whole blood collected in tempus tubes from patients with different spectra of TB disease. All patients were sampled prior to the initiation of any antimycoba...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-19442 | biostudies-arrayexpress
TranscriptomicsWhole blood transcriptional profiles of patients with active tuberculosis (TB) and other inflammatory and infectious diseases
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M. tuberculosis), is a major cause of morbidity and mortality worldwide and efforts to control TB are hampered by difficulties with diagnosis, prevention and treatment. Most people infected with M. tuberculosis remain asymptomat...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-22098 | biostudies-arrayexpress
GenomicsSphingobium sp. TB-6
Sphingobium sp. TB-6 Genome sequencing and assembly
PRJNA626513 | ENA
TranscriptomicsLung-resident myeloid-derived suppressor cells display dual functionality in experimental tuberculosis
Using cell-based approaches and experimental mouse models for pulmonary TB we unveiled MDSCs as new myeloid populations directly interacting with Mycobacterium tuberculosis (Mtb). MDSCs readily phagocytosed Mtb, released proinflammatory (IL-6, IL-1M-NM-1) and immunomodulatory (IL-10) cytokines while...
ORGANISM(S): Mus musculus 
2014-12-21 | E-GEOD-57124 | biostudies-arrayexpress
ProteomicsSERUM DATA FILES EMI TB PROTEOMICS
Five complete TMT10plex labellings including active TB patients and infected and uninfected contacts
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-04-01 | MSV000083645 | MassIVE
TranscriptomicsGene expression in M. tuberculosis and M. africanum infected tuberculosis patients prior to and following treatment
Differential gene expression in M. tuberculosis and M. africanum patients under TB treatment Gene expression analysis of whole blood RNA from tuberculosis patients prior to and following treatment
ORGANISM(S): Homo sapiens 
2015-06-05 | E-GEOD-62147 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human blood samples from HIV-infected and HIV-uninfected TB contacts
RNA-sequencing was performed on baseline blood samples from HIV-infected and HIV-uninfected asymptomatic adults with recent household exposure to an index case of infectious pulmonary tuberculosis (TB) and with detectable Mtb DNA in PBMC. Additional sequencing was also performed on follow-up blood s...
ORGANISM(S): Homo sapiens 
2025-01-05 | E-MTAB-13672 | biostudies-arrayexpress
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