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TranscriptomicsFemale human iPS cells retain an inactive X-chromosome
Comparison of human iPSC lines, ESC and fibroblasts to determine their expression patterns. All early passage female lines profiled expressed XIST RNA which is an indicator of an inactive X chromosome. Genes on the X-chromosome were also analyzed for overall levels of gene expression compared to h...
ORGANISM(S): Homo sapiens 
2010-08-18 | E-GEOD-22246 | biostudies-arrayexpress
TranscriptomicsRole of the reprogramming factors in inducing pluripotency
Induced pluripotent stem (iPS) cells can be obtained from fibroblasts by expression of Oct4, Sox2, Klf4, and c-Myc. To determine how these factors induce this change in cell identity, we carried out genomewide promoter analysis of their binding in iPS and partially reprogrammed cells. Most targets i...
ORGANISM(S): Mus musculus 
2010-05-06 | E-GEOD-14012 | biostudies-arrayexpress
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