Female human iPS cells retain an inactive X-chromosome

ABSTRACT: Comparison of human iPSC lines, ESC and fibroblasts to determine their expression patterns. All early passage female lines profiled expressed XIST RNA which is an indicator of an inactive X chromosome. Genes on the X-chromosome were also analyzed for overall levels of gene expression compared to human fibroblasts. hiPSC lines were generated and extracted for RNA with TriZOL and hybridization on Affymetrix arrays.

ORGANISM(S): Homo sapiens

SUBMITTER: Kathrin Plath 

PROVIDER: E-GEOD-22246 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress