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The genome sequencing of the tardigrade Ramazzottius varieornatus revealed a unique nucleo-some-binding protein, named Damage Suppressor (Dsup), which resulted to be crucial for the extraordinary abilities of tardigrades in surviving extreme stresses, such as UV. Evidence in Dsup transfected human c...
ORGANISM(S): Homo sapiens (Human) 
2023-07-31 | PXD037439 | Pride
PGC-1α plays a central role in maintaining the mitochondrial and energy metabolism homeostasis, linking external stimuli to the transcriptional co-activation of genes involved in adaptive and age-related pathways. The carboxyl-terminus encodes a serine/arginine-rich (RS) region and a putative RNA re...
ORGANISM(S): Homo sapiens (Human) 
2023-09-06 | PXD031189 | Pride
Three-dimensional nuclear architecture distinguishes thyroid cancer histotypes
The success of Enterococcus faecium and E. faecalis evolving as multi-resistant nosocomial pathogens is associated with their ability to acquire and share adaptive traits, including mobile genetic elements (MGE) encoding antimicrobial resistance. Here, we define the mobilome in representative succes...
ORGANISM(S): Enterococcus faecalis 
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