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TranscriptomicsComparing the effects of MITF on transcriptional regulation to the TEN1-ICD
We identified histidine triad nucleotide binding protein 1 (HINT1) as a human teneurin-1 ICD interaction partner in a yeast-2 hybrid screen. This interaction was confirmed in human cells, where HINT1 is known to inhibit the transcription of target genes by directly binding to transcription factors a...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-61705 | biostudies-arrayexpress
TranscriptomicsStudying the effects of the TEN1-ICD on transcriptional regulation
Teneurins are large type II transmembrane proteins that are necessary for the normal development of the central nervous system (CNS). While many studies highlight the significance of teneurins, especially during development, there is only limited information known about the molecular mechanisms of f...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-61704 | biostudies-arrayexpress
ProteomicsTeneurin-4 switches between self-recognition and canonical Latrophilin binding to direct neuronal migration
Cortical migration is a complex process in which neurons migrate along radial glial cells (RGC) to form functional layers. Teneurins (Ten1-4) play a role by interacting with Latrophilins (Lphn/ADGRL1-3). Teneurins are also known as cell adhesion molecules, but how homophilic and heterophilic Teneuri...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD075073 | Pride
Cortex development Teneurin Adhesion Neuronal migration Repulsion 
UnknownThe teneurin C-terminal domain possesses nuclease activity and is apoptogenic.
Not available
S-EPMC5898268 | biostudies-literature
UnknownReconstitution of synaptic junctions orchestrated by teneurin-latrophilin complexes.
Not available
S-EPMC11808628 | biostudies-literature
UnknownTeneurin Structures Are Composed of Ancient Bacterial Protein Domains.
Not available
S-EPMC6425310 | biostudies-literature
UnknownTeneurin trans-axonal signaling prunes topographically missorted axons.
Not available
S-EPMC10131173 | biostudies-literature
ProteomicsA novel role for Teneurin C-terminal Associated Peptide (TCAP) in the regulation of cardiac activity in the Sydney rock oyster, Saccostrea glomerata
Teneurin C-terminal associated peptide (TCAP) is an ancient bioactive peptide that is highly conserved in metazoans. TCAP administration reduces cellular and behavioural stress in vertebrate and urochordate models, yet despite numerous studies in higher animals, there is limited knowledge of its rol...
ORGANISM(S): Saccostrea glomerata 
2023-01-27 | PXD039155 | Pride
Metabolism Transcriptome Teneurin Heart Tcap Heart rate Oysters Stress 
UnknownThe structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers.
Not available
S-EPMC10240212 | biostudies-literature
ProteomicsStructurally Exclusive Teneurin Complexes Orchestrate Divergent Programs in Early Cortical Development
Cortical migration is a complex process in which neurons migrate along radial glial cells (RGC) to form functional layers. Teneurins (Ten1-4) play a role by interacting with Latrophilins (Lphn/ADGRL1-3). Teneurins are also known as cell adhesion molecules, but how homophilic and heterophilic Teneuri...
ORGANISM(S): Homo sapiens (Human) 
2026-02-25 | PXD058769 | Pride
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