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TranscriptomicsHypothalamic gene expression profile indicates a reduction in G-protein signaling in the wfs1 mutant mice
WFS1 gene is coding protein with unknown function but its functional deficiency causes different neuropsychiatric and neuroendocrine syndromes. In the present study we aimed to find the functional networks influenced by the Wfs1 deficiency in the hypothalamus. We performed gene expression profiling ...
ORGANISM(S): Mus musculus 
2011-11-02 | E-GEOD-33372 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of temporal lobes of wfs1 deficient mice
Aim of present study was to describe the changes induced deletion of the Wfs1 gene in the temporal lobe of mice. Mutant mice were backcrossed to two different genomic backgrounds in order to exclude confounding foreign genomic background influence. Samples from temporal lobes were analyzed by using ...
ORGANISM(S): Mus musculus 
2010-04-06 | E-GEOD-15293 | biostudies-arrayexpress
TranscriptomicsEffect of chronic valproic acid treatment on hepatic gene expression profile in Wfs1 knockout mouse.
Aim of the present study was to compare the effect of chronic VPA treatment in wild type and Wfs1 knockout mice on hepatic gene expression profile. Wild type, Wfs1 heterozygous and homozygous mice were treated with VPA for three months (300 mg/kg i.p. daily) and gene expression profiles in liver wer...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-55143 | biostudies-arrayexpress
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