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One antifungal agent, terbinafine(TRB), has specific activity against dermatophytes.A cDNA microarray was constructed from the expressed sequence tags (ESTs) of different developmental stages, and transcriptional profiles of the responses to TRB were determined. Some class-specific and mechanism-ind...
ORGANISM(S): Trichophyton rubrum 
One antifungal agent, terbinafine(TRB), has specific activity against dermatophytes.A cDNA microarray was constructed from the expressed sequence tags (ESTs) of different developmental stages, and transcriptional profiles of the responses to TRB were determined. Some class-specific and mechanism-ind...
ORGANISM(S): Trichophyton rubrum 
2008-02-04 | GSE6951 | GEO
Targeting mitochondrial stress responses: Terbinafine and Miglustat as novel lifespan and healthspan modulators
The transcriptional profile of Trichophyton rubrum co-cultured with human keratinocytes shows new insights about gene modulation by terbinafine.
Mitochondria are key regulators of cellular homeostasis, aging, and age-related diseases. This study investigates the mitochondrial stress response (MSR) and its role in longevity by identifying Terbinafine and Miglustat as novel mitochondrial stress inducers in Caenorhabditis elegans. Using a two-s...
ORGANISM(S): Caenorhabditis elegans 
2026-02-27 | GSE290712 | GEO
RNA-seq of Trichophyton rubrum treated by terbinafine
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