Sort   by:  
 Page size 
GenomicsThe Histone Methyltransferase Wbp7 Controls Macrophage Function through GPI Glycolipid Anchor Synthesis. [ChIP_seq]
Histone methyltransferases catalyze site-specific deposition of methyl groups, enabling recruitment of transcriptional regulators. In mammals, trimethylation of lysine 4 in histone H3, a modification localized at the transcription start sites of active genes, is catalyzed by six enzymes (SET1a and S...
ORGANISM(S): Mus musculus 
2012-04-09 | E-GEOD-30972 | biostudies-arrayexpress
TranscriptomicsA dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-56123 | biostudies-arrayexpress
GenomicsA dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.
The transcription factor (TF) interferon regulatory factor 8 (IRF8) controls both developmental and inflammatory stimulus-inducible genes in macrophages, but the mechanisms underlying these two different functions are largely unknown. One possibility is that these different roles are linked to the a...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-56121 | biostudies-arrayexpress
TranscriptomicsA dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.
IThe transcription factor (TF) interferon regulatory factor 8 (IRF8) controls both developmental and inflammatory stimulus-inducible genes in macrophages, but the mechanisms underlying these two different functions are largely unknown. One possibility is that these different roles are linked to the ...
ORGANISM(S): Mus musculus 
2015-01-30 | E-GEOD-56122 | biostudies-arrayexpress
GenomicsHDAC3 requirement for the inflammatory gene expression program in macrophages [ChIP_Seq]
Pan-Hdac inhibitors (HDACi) are endowed with a potent anti-inflammatory activity, but the relative role of each of the eleven Hdac proteins sensitive to HDACi to the inflammatory gene expression program is unknown. Using an integrated genomic approach we found that Hdac3-deficient macrophages are un...
ORGANISM(S): Mus musculus 
2012-07-08 | E-GEOD-33163 | biostudies-arrayexpress
TranscriptomicsThe Histone Methyltransferase Wbp7 Controls Macrophage Function through GPI Glycolipid Anchor Synthesis. [Expression Profile]
Histone methyltransferases catalyze site-specific deposition of methyl groups, enabling recruitment of transcriptional regulators. In mammals, trimethylation of lysine 4 in histone H3, a modification localized at the transcription start sites of active genes, is catalyzed by six enzymes (SET1a and S...
ORGANISM(S): Mus musculus 
2012-04-08 | E-GEOD-30971 | biostudies-arrayexpress
TranscriptomicsHDAC3 requirement for the inflammatory gene expression program in macrophages [gene expression]
Pan-Hdac inhibitors (HDACi) are endowed with a potent anti-inflammatory activity, but the relative role of each of the eleven Hdac proteins sensitive to HDACi to the inflammatory gene expression program is unknown. Using an integrated genomic approach we found that Hdac3-deficient macrophages are un...
ORGANISM(S): Mus musculus 
2012-07-08 | E-GEOD-33162 | biostudies-arrayexpress
TranscriptomicsHDAC3 requirement for the inflammatory gene expression program in macrophages
This SuperSeries is composed of the following subset Series: GSE33162: HDAC3 requirement for the inflammatory gene expression program in macrophages [gene expression] GSE33163: HDAC3 requirement for the inflammatory gene expression program in macrophages [ChIP_Seq] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-07-08 | E-GEOD-33164 | biostudies-arrayexpress
GenomicsThe Histone Methyltransferase Wbp7 Controls Macrophage Function through GPI Glycolipid Anchor Synthesis
This SuperSeries is composed of the following subset Series: GSE30971: The Histone Methyltransferase Wbp7 Controls Macrophage Function through GPI Glycolipid Anchor Synthesis. [Expression Profile] GSE30972: The Histone Methyltransferase Wbp7 Controls Macrophage Function through GPI Glycolipid Anchor...
ORGANISM(S): Mus musculus 
2012-04-08 | E-GEOD-30973 | biostudies-arrayexpress
GenomicsTranscription of mammalian cis-regulatory elements is restrained by actively enforced early termination [ChIP-Seq]
Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRNAs generated by cis-regulatory elements are largely unknown. Here, we show that the adapter protein ...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-66951 | biostudies-arrayexpress
Sort   by:  
 Page size