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ProteomicsShared and Distinct Mechanisms of UBA1 Inactivation Across Different Diseases
UBA1 initiates most cellular ubiquitin signaling by activating and transferring ubiquitin to tens of E2 enzymes. Clonally acquired UBA1 missense mutations cause a severe inflammatory-hematologic overlap disease called VEXAS (vacuoles, E1, X-linked autoinflammatory, somatic) syndrome. Despite extensi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092914 | MassIVE
MetabolomicsGNPS - R_OM_Metapyo_32_CF_patients_HILIC_neg
idem R_OM_Metapyo_32_CF_patients_C18_pos we analyzed the metabolome content by untargeted HPLC/HRMS (see supplementary information). Isolates were first grown in synthetic CF medium 2 (SCFM2), a culture medium designed to mimick the nutritional conditions in CF pulmonary mucus (Turner et al. 2014). ...
ORGANISM(S): Pseudomonas Aeruginosa 
2020-01-10 | MSV000084791 | GNPS
MetabolomicsGNPS - R_OM_Metapyo_32_CF_patients_C18_pos
we analyzed the metabolome content by untargeted HPLC/HRMS (see supplementary information). Isolates were first grown in synthetic CF medium 2 (SCFM2), a culture medium designed to mimick the nutritional conditions in CF pulmonary mucus (Turner et al. 2014). Intracellular metabolic extracts of mid-l...
ORGANISM(S): Pseudomonas Aeruginosa (ncbitaxon:287) 
2020-01-10 | MSV000084790 | GNPS
ProteomicsR_OM_Metapyo_32_CF_patients_HILIC_neg
idem R_OM_Metapyo_32_CF_patients_C18_pos we analyzed the metabolome content by untargeted HPLC/HRMS (see supplementary information). Isolates were first grown in synthetic CF medium 2 (SCFM2), a culture medium designed to mimick the nutritional conditions in CF pulmonary mucus (Turner et al. 2014). ...
ORGANISM(S): Pseudomonas Aeruginosa 
2020-01-10 | MSV000084791 | MassIVE
ProteomicsR_OM_Metapyo_32_CF_patients_C18_pos
we analyzed the metabolome content by untargeted HPLC/HRMS (see supplementary information). Isolates were first grown in synthetic CF medium 2 (SCFM2), a culture medium designed to mimick the nutritional conditions in CF pulmonary mucus (Turner et al. 2014). Intracellular metabolic extracts of mid-l...
ORGANISM(S): Pseudomonas Aeruginosa (ncbitaxon:287) 
2020-01-10 | MSV000084790 | MassIVE
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