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TranscriptomicsBovine pre-transfer endometrium and embryo transcriptome fingerprints as predictors of pregnancy success after embryo transfer (endometrial study)
The aberrant gene expression in the uterine endometrium and embryo has been the major causes of pregnancy failure in cattle. Therefore, selecting cows having adequate endometrial receptivity and embryos of better developmental competence based on the gene expression could increase the number of calv...
ORGANISM(S): Bos taurus 
2010-04-07 | E-GEOD-20974 | biostudies-arrayexpress
TranscriptomicsPlacental gene expression in pregnancies established after the transfer of day 7 blastocysts derived from in vitro (IVP), somatic cell nuclear transfer (SCNT) and in vivo (AI) embryos
Aberrant placental gene expression associated with culture condition and/or deficiencies in transcriptome reprogramming are hypothesized to be the major cause of SCNT and IVP inefficiencies. Therefore, the main objective of this study was to invesitgate the dysregulated genes, molecular pathways and...
ORGANISM(S): Bos taurus 
2012-06-05 | E-GEOD-38512 | biostudies-arrayexpress
TranscriptomicsWhole genome bisulfite sequencing of bovine oocytes from metabolically divergent lactating cows and nulliparous heifers
Lactating cows experience transient metabolic stresses during postpartum which results in abnormal concentrations of non-esterified fatty acids and beta-hydroxybutyrate that can impact oocyte maturation and ultimately reproductive success. We hypothesize that metabolic challenges in lactating cows ...
ORGANISM(S): Bos taurus 
2021-11-30 | E-MTAB-8191 | biostudies-arrayexpress
TranscriptomicsWhole genome bisulfite sequencing of bovine morula derived from metabolically divergent dairy cows
Lactating cows experience transient metabolic stresses during postpartum which results in abnormal concentrations of non-esterified fatty acids and beta-hydroxybutyrate that can affect embryo-maternal communication and ultimately reproductive success. We hypothesize that metabolic challenges in lact...
ORGANISM(S): Bos taurus 
2021-11-30 | E-MTAB-8239 | biostudies-arrayexpress
TranscriptomicsGene expression in rat ovaries treated with DHT
Polycystic ovarian syndrome (PCOS) is an endocrine disorder of the reproductive and metabolic axis in women during the reproductive age. In this study, we used a rat model exhibiting reproductive and metabolic abnormalities similar to human PCOS to unravel the molecular mechanisms underlining this ...
ORGANISM(S): Rattus norvegicus 
2016-07-03 | E-GEOD-59456 | biostudies-arrayexpress
TranscriptomicsBovine pre-transfer endometrium and embryo transcriptome fingerprints as predictors of pregnancy success after embryo transfer (embryo study)
The aberrant gene expression in the uterine endometrium and embryo has been the major causes of pregnancy failure in cattle. Therefore, selecting cows having adequate endometrial receptivity and embryos of better developmental competence based on the gene expression could increase the number of calv...
ORGANISM(S): Bos taurus 
2010-06-05 | E-GEOD-21047 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of endometrium and the bovine preimplantative embryo to subclinical inflamation of the uterine environment
Combining the cytological as well as gene expression changes in the endometrium is required to understand the effects of subclinical endometritis on endometrium as well as embryo. Hence, the present study was aimed to investigate the gene expression profiles of subclinical endometrium as well the ef...
ORGANISM(S): Bos taurus 
2011-11-09 | E-GEOD-33496 | biostudies-arrayexpress
TranscriptomicsRNA deep sequencing reveals novel candidate genes and polymorphisms in boar testis and liver tissues with divergent androstenone levels.
Boar taint described as an offensive odor that is released while cooking pork. Androstenone, a steroid mainly synthesized in testis and metabolized in liver is one of the major causes of boar taint. The aim of the present study was to investigate transcriptome differences in boar testis and liver ti...
ORGANISM(S): Sus scrofa 
2013-02-09 | E-GEOD-44171 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of bovine day 16 embryos obtained from SCNT and IVP pregnancies
In vitro production systems, as well as cloning technology, may lead to persistent aberrations of gene expression patterns during embryonic and fetal development. In order to get a global overview of gene expression alteration induced by in vitro environment and somatic cell nuclear transfer, we per...
ORGANISM(S): Bos taurus 
2012-08-14 | E-GEOD-40101 | biostudies-arrayexpress
UnknownThe African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa.
Not available
S-EPMC11872788 | biostudies-literature
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