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GenomicsGenome-wide DNA methylation profiling reveals epigenetic changes in the rat nucleus accumbens associated with cross-generational effects of adolescent THC exposure
Drug exposure during critical periods of development is known to have lasting effects, increasing one’s risk for developing mental health disorders. Emerging evidence has also indicated the possibility for drug exposure to even impact subsequent generations. Our previous work demonstrated that adole...
ORGANISM(S): Rattus norvegicus 
2015-06-19 | E-GEOD-69984 | biostudies-arrayexpress
GenomicsTHC Protect
Thc protect llc
PRJNA1097369 | ENA
ProteomicsProteomic consequences of early postnatal, chronic THC exposure for the adolescent and adult hippocampus
This study aims to identify the proteomic targets of THC in the early postnatal hippocampus of developing mice. Therefore, early postnatal C57Bl/6 mice (P5) were exposed daily and for 30 days to plant extracted THC (either 1 mg/kg or 5 mg/kg) or vehicle solution (saline with 3% Tween® 80) for the co...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-09 | PXD010802 | Pride
Hippocampus Mouse brain development Thc 
TranscriptomicsmiRNA profiling of Macaca mulatta intact duodenum samples following chronic Delta9 Tetrahydrocannabinol (M-NM-^T9-THC) treatment to SIV infected rhesus macaques
The study describes miRNA expression in intact duodenum following chronic delta 9 tetrahydrocannabinol (M-NM-^T9-THC) administration to SIV-infected rhesus macaques. Chronic M-NM-^T9-THC administration to uninfected macaques significantly and positively modulated intestinal miRNA expression by incre...
ORGANISM(S): Macaca mulatta 
2014-11-19 | E-GEOD-61654 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat primary astrocytes treated with vehicle or delta-9-tetrahydrocannabinol (THC) to identify response to THC treatment
Rat primary astrocytes- were treated with vehicle or delta-9-tetrahydrocannabinol (THC), total RNA was isolated and gene expression in response to THC treatment was studied.
ORGANISM(S): Rattus norvegicus 
2006-03-05 | E-MEXP-576 | biostudies-arrayexpress
GenomicsFlavobacterium psychrophilum strain:THC 02-90
Flavobacterium psychrophilum strain:THC 02-90 Genome sequencing and assembly
PRJNA262099 | ENA
ProteomicsDiscontinuation of chronic delta-9-tetrahydrocannabinol diminishes impact on male fertility and the sperm epigenome in rhesus macaques
Cannabis is commonly used amongst reproductive age males. Our group and others have shown that chronic delta-9-tetrahydrocannabinol (THC) use adversely impacts male fertility, but less is known about the potential reversibility of these changes. Our study’s objective was to determine if THC disconti...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2023-05-18 | PXD039802 | Pride
Cannabis Quantitative proteomics Male fertility Seminal fluid Rhesus macaque Mass spectrometry Isobaric labeling 
TranscriptomicsMicroarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells
Cannabinoids are known to exert immunosuppressive activities. However, the mechanisms which contribute to these effects are unknown. Using lipopolysaccharide (LPS) to activate BV-2 microglial cells, we examined how Δ9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, and can...
ORGANISM(S): Mus musculus 
2015-07-09 | E-GEOD-70689 | biostudies-arrayexpress
GenomicsscRNA-seq of mouse colon after THC administration
scRNA-seq of mouse colon after THC administration
PRJNA655180 | ENA
GenomicsTHC Microbiome and Weight Loss
Microbiome Variations Induced by delta 9 - Tetrahydrocannabinol (THC) Predicts Weight Reduction in Obese Mice
PRJEB76955 | ENA
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