The Internal Medicine Study Group

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Unknown (20086)
Metabolomics (226)
Proteomics (129)
Transcriptomics (82)
Genomics (50)
Genomic (7)
Clinical (7)
Multiomics (1)

Organisms

Homo sapiens (88)
Mus musculus (36)
Rattus norvegicus (12)
Bos taurus (11)
Escherichia coli (11)
Canis lupus familiaris (6)
Plasmodium falciparum (3)
Sus scrofa domesticus (3)
Oryctolagus cuniculus (2)
Candida albicans (2)
Danio rerio (2)
Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S (2)
Staphylococcus aureus (2)
Saccharomyces cerevisiae (2)
Canis lupus (2)
Gallus gallus (2)
Mycobacterium tuberculosis H37Rv (2)
Escherichia coli APEC O1 (1)
Francisella tularensis subsp. novicida (1)
Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 (1)
Yersinia pseudotuberculosis (1)
Trypanosoma cruzi (1)
Medicago truncatula (1)
Escherichia coli K-12 (1)
Arabidopsis thaliana (1)
Acyrthosiphon pisum (1)
Bacteria (1)
Cavia porcellus (1)
Coxsackievirus (1)
Cricetulus griseus (1)

Organisms

Homo sapiens (20)
Mus musculus (15)
Rattus norvegicus (4)
Papio hamadryas (2)
Canis lupus familiaris (2)

Repository

MetaboLights (226)
pride (111)
biostudies-arrayexpress (81)
ENA (46)
MassIVE (14)
dbGaP (7)
EGA (3)
geo (2)
iProX (2)
jPOST (1)
LINCS (1)

Tissue

Cell culture (19)
Brain (11)
Blood plasma (9)
Blood serum (9)
Urine (5)
Epithelial cell (4)
Heart (4)
Liver (4)
B cell (3)
Cerebrospinal fluid (3)
Lung (3)
Sperm (3)
Extracellular vesicle (2)
Intestine (2)
Kidney (2)
Neuron (2)
Oocyte (2)
Saliva (2)
Skin (2)
Stem cell (2)
Sweat (2)
Arterial system (1)
Bladder (1)
Blood cell (1)
Blood vessel (1)
Bone marrow (1)
Cardiac muscle cell (1)
Culture condition: dark grown cells (1)
HEK-293T cell (1)
T cell (1)

Disease

Colorectal Neoplasms (5)
Disease free (5)
Alzheimer's disease (2)
Babesiosis (2)
Cardiovascular system disease (2)
Colon cancer (2)
Colorectal cancer (2)
Epilepsy (2)
Medulloblastoma (2)
Urinary bladder cancer (2)
Normal (1)
Colorectal cancer survivors (1)
Endocrine gland, unspecified (1)
Aortic valve stenosis (1)
Bacterial infectious disease (1)
Breast cancer (1)
Cerebrovascular disease (1)
Cervix carcinoma (1)
Chronic kidney disease (1)
Coronavirus infectious disease (1)
Cystic fibrosis (1)
Degenerative disc disease (1)
Diabetes (1)
Duchenne muscular dystrophy (1)
Enteritis (1)
Follicular adenoma (1)
Head and neck cancer (1)
Kidney cancer (1)
Lung cancer (1)
Lung carcinoma (1)

Technology Type

Mass spectrometry (139)
Mass Spectrometry (111)
Mass spectrometry assay (77)
Shotgun proteomics (72)
Bottom-up proteomics (25)
NMR spectroscopy (10)
Data-dependent acquisition (9)
Data-independent acquisition (5)
SWATH MS (5)
Affinity purification coupled with mass spectrometry proteomics (3)
SRM/MRM (3)
NMR spectroscopy assay (2)
All-ion fragmentation (2)
Gel-based experiment (2)
Mass spectrometry (1)
P100 (1)
DiaPASEF (1)
HDMSE (1)
Mass spectrometry imaging (1)
PAcIFIC (1)
Top-down proteomics (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (64)
Liquid Chromatography MS - negative - reverse phase (59)
Liquid Chromatography MS - negative - reverse-phase (40)
Liquid Chromatography MS - positive - reverse-phase (36)
Liquid Chromatography MS - negative - hilic (24)
Liquid Chromatography MS - positive - hilic (22)
Gas Chromatography MS - positive (10)
Exactive (Thermo Scientific) (9)
Gas Chromatography MS - (9)
Liquid Chromatography MS - positive - HILIC (8)
Q Exactive (7)
Liquid Chromatography MS - alternating - reverse phase (7)
Nuclear Magnetic Resonance (NMR) - (7)
Illumina NovaSeq 6000 (5)
Liquid Chromatography MS - alternating - reverse-phase (5)
Liquid Chromatography MS - negative - HILIC (5)
Bruker (4)
Liquid Chromatography MS - (4)
NextSeq 500 (2)
Q-Exactive Plus (Thermo Fisher Scientific) LC-MS/MS (2)
MGISEQ-2000RS (1)
GeneChip Hybridization Oven 645 (1)
GeneChip Scanner 3000 7G (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 3000 (1)
Bruker Daltonics instrument model (1)
LTQ FT (1)
LTQ Orbitrap Elite (1)
Orbitrap Fusion (1)
Q Exactive HF (1)

Publication Date

2026 (94)
2025 (56)
2022 (47)
2023 (33)
2024 (30)
2021 (28)
2018 (18)
2019 (18)
2010 (16)
2017 (16)
2020 (15)
2016 (13)
2011 (10)
2015 (9)
2013 (8)
2008 (8)
2014 (5)
2012 (5)
2007 (5)
2009 (4)

CHEBI ID

CHEBI:15428 (33)
CHEBI:16750 (31)
CHEBI:17368 (31)
CHEBI:17568 (31)
CHEBI:28044 (31)
CHEBI:30769 (31)
CHEBI:17596 (30)
CHEBI:15756 (29)
CHEBI:16811 (29)
CHEBI:17822 (29)
CHEBI:15891 (28)
CHEBI:16335 (28)
CHEBI:16737 (28)
CHEBI:25017 (28)
CHEBI:27897 (28)
CHEBI:15741 (27)
CHEBI:16015 (26)
CHEBI:16414 (26)
CHEBI:17203 (26)
CHEBI:17295 (26)
CHEBI:17351 (26)
CHEBI:17895 (26)
CHEBI:18186 (26)
CHEBI:18237 (26)
CHEBI:18257 (26)
CHEBI:16449 (25)
CHEBI:16704 (25)
CHEBI:16828 (25)
CHEBI:16919 (25)
CHEBI:18211 (25)

Metabolite Name

Creatine (43)
Taurine (41)
Adenosine (40)
Hypoxanthine (40)
Adenine (39)
Creatinine (39)
Uracil (39)
Inosine (37)
Xanthine (37)
Uridine (36)
Choline (35)
Cytosine (35)
Guanine (35)
Guanosine (35)
Citrulline (33)
Riboflavin (32)
Glycine (30)
Histamine (30)
L-Tyrosine (30)
Ornithine (30)
L-Proline (29)
Pantothenic acid (29)
Betaine (28)
Citric acid (28)
Cytidine (28)
Taurocholic acid (28)
4-Hydroxybenzaldehyde (27)
Alanine (27)
Glutamine (27)
L-Glutamine (27)

First Public Date

2014 (13)
2026 (7)
2025 (4)
2024 (4)
2023 (4)
2021 (4)
2022 (3)
2019 (3)
2017 (2)
2020 (1)
2018 (1)

Modification

+3amu) (1)
N6 (1)

Study status

Completed (5)
Not provided (1)
Recruiting (1)

Study type

Transcription profiling by array (58)
RNA-seq of coding RNA (8)
Interventional (7)
Unknown experiment type (2)
ChIP-chip by tiling array (2)
Cell line - High-throughput sequencing (2)
Methylation profiling by array (2)
One-color microarray (1)
Animal - High-throughput sequencing (1)
ChIP-chip by array (1)
Comparative genomic hybridization by array (1)
Other (1)
RNA-seq of coding RNA from single cells (1)
RNA-seq of total RNA (1)

Release Date

2022 (2903)
2025 (2464)
2023 (2453)
2021 (2357)
2024 (2123)
2020 (1638)
2019 (1232)
2018 (977)
2017 (783)
2016 (698)
2015 (602)
2014 (488)
2026 (360)
2013 (307)
2012 (208)
2011 (175)
2010 (153)
2009 (93)
2008 (66)
2007 (30)
2006 (22)
2005 (13)
2002 (7)
2003 (4)
2004 (3)
2001 (3)
2000 (2)
1998 (2)
1999 (1)

Lab affiliation

Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06520, USA. Systems Biology Institute, Yale University, New Haven, CT 06516, USA (7)
Internal Diseases Clinic, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia (4)
Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06520, USA. Systems Biology Institute, Yale University, New Haven, CT 06516, USA (3)
General Manager of PROMEC Department of Clinical and Molecular Medicine +4773598508 +4772573342 Laboratoriesenteret, 231.04.008, Øya, Erling Skjalgssons gate 1 Norway (2)
Keck MS & Proteomics Resource Yale School of Medicine (2)
Laboratory of Mass Spectrometry-Director MolSys Research Unit-Director CART (Center for Analytical Research and Technology)-Director Liège Université, Liège, Belgium (2)
Laboratory of Proteomics, Internal Diseases Clinic, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia (2)
1Dept. of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205 2Dept. of Environmental and Occupational Health, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205 (1)
AHF&RSS, Radiation Biology & Health Sciences Division, Bio-Sciences Group, Bhabha Atomic Research Centre, Mumbai 400 085, India. (1)
Ahmet Hoke M.D., Ph.D. FRCPC Professor, Neurology and Neuroscience Director, Neuromuscular Division Director, Merkin Peripheral Neuropathy and Nerve Regeneration Center Editor-in-Chief, Experimental Neurology Johns Hopkins School of Medicine 855 N. Wolfe St., Rangos 248 Baltimore, MD, 21205 USA (1)
Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP), Portuguese Oncology Institute of Porto, Porto, Portugal (1)
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Bennett Laboratory Mass Spectrometry & Proteomics (1)
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria (1)
Center for Medical Biotechnology, VIB, 9000 Ghent, Belgium. Department for Biomolecular Medicine, Ghent University, 9000 Ghent, Belgium. VIB Proteomics Core, VIB, 9000 Ghent, Belgium. (1)
Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China; (1)
Center for Research Innovation and Bioinformatics, Faculty of Medical Technology, Mahidol University, Nakhon Pathom, Thailand (1)
Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, 3168, Australia. (1)
Department II of Internal Medicine and Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany (1)
Department for Proteomics, Center for Translational and Clinical Research, School of Medicine, University of Zagreb Department of Anatomy “Drago Perović”, School of Medicine, University of Zagreb (1)
Department of Animal Sciences, Robert H. Smith Faculty of Agriculture, Food and Environment, the Hebrew University, Rehovot 76100, Israel Center of Excellence in Agriculture and Environmental Health, the Hebrew University, Rehovot 76100, Israel (1)
Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine (1)
Department of Biomedical Sciences, unit of Diagnostic Bacteriology, Institute of Tropical Medicine (1)
Department of Biomolecular Medicine, Faculty of Medicine & Health Sciences, Ghent University, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium (1)
Department of Biomolecular Medicine, Faculty of Medicine & Health Sciences, Ghent University, Belgium; Cancer Research Institute Ghent (CRIG), Ghent, Belgium. (1)
Department of Biomolecular Medicine, Ghent University, Ghent, Belgium VIB Center for Medical Biotechnology, VIB, Ghent, Belgium (1)
Department of Cellular & Molecular Physiology, Yale School of Medicine Systems Biology Institute, Yale University (1)
Department of Cellular & Molecular Physiology, Yale School of Medicine Systems Biology Institute, Yale University (1)
Department of Clinical and Molecular Medicine Faculty of Medicine and Health Sciences Norwegian University of Science and Technology Trondheim, Norway (1)
Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology (NTNU), PO Box 8905, N-7491, Trondheim, Norway Phone: +47 72573075, (1)
Department of General Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education (1)

Location

Switzerland (2)
France (1)
Germany (1)
Malaysia (1)

Keyword

Early Detection of Cancer (1)
General practitioners (1)
Intervention Studies (1)
Motivational interviewing (1)
Randomized Controlled Trial (1)

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Metagenomics and Metabolomics Integrated to Explore the Protective Mechanisms of Mongolian Medicine Zadi-5 in Myocardial Ischemic Model Rats

Myocardial ischemia(MI) is a pathological state of abnormal energy metabolism due to insufficient blood and oxygen supply to the coronary arteries. The 'gut-heart axis' theory plays an important role in myocardial ischemia occurrence, mechanism, prevention, and cure. Traditional Mongolian medicin...

2026-01-27 | MTBLS13780 | MetaboLights

Mongolian medicine Wulanwendusu-11 ameliorates myocardial ischemia-reperfusion injury in association with the modulation of intestinal microbiota and associated metabolic pathways

Abstract

Objective: Wulanwendusu-11 (WLWDS-11), a traditional Mongolian medicinal formula, is commonly used for the treatment of Cardiovascular diseases. However, its therapeutic material basis and in vivo metabolic profile in the context of chronic myocardial ischemia-reperfusion injury (M...

2025-11-22 | MTBLS13370 | MetaboLights

Comparison analysis of metabolite profiling in seeds and bark of Ulmus parvifolia, a Chinese medicine species

Ulmus parvifolia (U. parvifolia) was traditionally used in the treatment of some diseases such as inflammation, diarrhea and fevers. With the wide application of molecular biotechnology in plant development and utilization, the pharmaceutical value and chemical composition of th...

2024-01-09 | MTBLS4572 | MetaboLights

Education Indicators for Internal Medicine Point-of-Care Ultrasound: a Consensus Report from the Canadian Internal Medicine Ultrasound (CIMUS) Group.

Not available

S-EPMC6816798 | biostudies-literature

Study on the mechanism of p-hydroxybenzyl alcohol against OGD/R damage based on metabonomic analysis

Gastrodia elata Blume (GE) has been widely used to treat various central and peripheral nerve diseases, and P-Hydroxybenzaldehyde (PHBA) is one of the indicative components of GE brain protection. Since the previous study of our group found that PHBA has a good effect on protecting mitoc...

2024-07-04 | MTBLS7870 | MetaboLights

Based on untargeted metabolomics and metagenomics: a study on the mechanism of Miao ethnomedicine Zingiber mioga (Thunb.) Rosc. in treating slow transit constipation

A rat model of slow transit constipation (STC) was induced by loperamide hydro-chloride to explore the therapeutic mechanism of Zingiber mioga (Thunb.) Rosc. (RH) using integrated metabolomic and metagenomic approaches. Thirty-six Sprague–Dawley (SD) rats were randomly assigned to 6 gro...

2026-02-11 | MTBLS13888 | MetaboLights

Research activities in general medicine: a scoping survey by the Internal Medicine Society of Australia and New Zealand.

Not available

S-EPMC9543186 | biostudies-literature

Internal Medicine Resident Perceptions of Patients with Substance Use Disorder After Attending a Mutual Support Group Meeting.

Not available

S-EPMC7080948 | biostudies-literature

Relationship Between Vitamin D Levels and Psychological Stress-Induced Asthma Prevalence: An Untargeted Metabolomics Study Combined with the NHANES Database

The incidence of psychological stress–induced asthma has been increasing annually, and numerous previous studies have shown that vitamin D is associated with the development of asthma as well as anxiety and depression. However, no studies to date have clarified the relationship between vitamin D and...

2026-04-16 | MTBLS14208 | MetaboLights

Identification of pre-diagnostic lipid sets associated with liver cancer risk using untargeted lipidomics and chemical set analysis – a nested case-control study within the ATBC cohort

In pre-disposed individuals, a reprogramming of the hepatic lipid metabolism may support liver cancer initiation. We conducted a high-resolution mass spectrometry based untargeted lipidomics analysis of pre-diagnostic serum samples from a nested case-control study (219 liver cancer cases and 219 ...

2023-09-18 | MTBLS7776 | MetaboLights

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